This research aimed to investigate predicting factors of fatigue in post-stroke patients in early phase, including hemoglobin level, nutritional status, insomnia and physical activity. One hundred patient with ischemic and hemorrhagic stroke were recruited by a purposive sampling. Participants were followed up at out-patient departments of stroke clinics from Chulalongkorn Memorial Hospital and Police Hospital. The research instruments included the demographic data questionnaire and the illness data form, Fatigue Severity Index, The mini nutritional assessment, Insomnia Severity Index and Global Physical Activity Questionnaire. These instruments were tested for their content validity by a panel of experts. Instrument was tested by using reliability Cronbach's alpha coefficients obtained at .86, .80, .86 and .78, respectively. Data were analyzed by using descriptive statistics, Point Biserial correlation coefficients, Pearson's product moment correlation coefficient and stepwise multiple regression.The major findings were as follows:1. 63% of post-stroke patients in early phase had fatigue (Mean = 4.42, S.D. = 1.63)2. Hemoglobin levels and insomnia were statistically significant predictors of fatigue in post-stroke patients in early phase at the level of 05. The power predictor was 30%. The equation derived from the standardized score was:(ZFatigue) = -.42Z hemoglobin levels + .21Z insomnia.
