Title | Genotoxicity and DNA Repair [electronic resource] : A Practical Approach / edited by L. María Sierra, Isabel Gaivão |
---|---|
Imprint | New York, NY : Springer New York : Imprint: Humana Press, 2014 |
Connect to | http://dx.doi.org/10.1007/978-1-4939-1068-7 |
Descript | XII, 483 p. 70 illus., 42 illus. in color. online resource |
Ames Test (Bacterial Reverse Mutation Test): Why, When, and How to Use -- The Ames II and Ames MPF Penta I Assay: A Liquid Microplate Format Modification of the Classic Ames Test -- Revised Procedure of the Bacterial Reverse Mutation Test for Genotoxic Evaluation of Nanoparticles -- The Control of Hydrophobic Compound Exposure in In Vitro Tests for Genotoxicity -- The In Vitro Micronucleus Assay and FISH Analysis -- The In Vivo Rodent Micronucleus Test -- Chromosomal Aberration Test Utilities In Vitro and In Vivo -- Chromosome Painting of Mouse Peripheral Blood and Spleen Tissues -- T-Cell Receptor Mutation Assay for Monitoring Human Genotoxic Exposure -- The Human RBC PIG-A Gene Mutation Assay -- The Applicable Use of the HPRT Gene Mutation Assay as a Practical Tool in Mutagenesis and DNA Repair Studies -- The Comet Assay: High Throughput Use of FPG -- The Comet Assay In Vivo in Humans -- Analysis of Nanoparticle-Induced DNA Damage by the Comet Assay -- The Comet Assay in Drosophila: Neuroblast and Haemocyte Cells -- The SMART Assays of Drosophila: Wings and Eyes as Target Tissues -- Testing the Genotoxic Potential of Nanomaterials Using Drosophila -- Transgenic Rodent Gene Mutation Assay in Somatic Tissues -- The Mouse Lymphoma Assay -- Bhas 42 Cell Transformation Assay for Genotoxic and Non-Genotoxic Carcinogens -- Methods for Measuring DNA Repair: Introduction and Cellular Repair -- A Standardized Protocol for the In Vitro Comet-Based DNA Repair Assay -- Use of the Comet Assay to Study DNA Repair in Drosophila melanogaster -- Use of RNA Interference to Study DNA Repair -- The LacZ Plasmid-Based Transgenic Mouse Model: An Integrative Approach to Study the Genotoxicity of Nanomaterials