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TitleMonophasic Action Potentials [electronic resource] : Basics and Clinical Application / edited by Michael R. Franz, Claus Schmitt, Bernhard Zrenner
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1997
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Descript X, 241 p. 8 illus. in color. online resource


Over the last two decades monophasic action potential (MAP) recording has matured into a technique that provides a link between basic and clinical electrophysiology. International experts present exciting data on MAP recording techniques, the mechanism and interpretation of MAPs, and novel aspects of repolarization-related arrhythmias


I Historical Development and MAP Recording Technique -- Historical Development of the Monophasic Action Potential Recording Technique -- Monophasic Action Potential Recordings: What Are They, How Can They Be Recorded, What Is Their Use? -- Basic Biophysical Characteristics of Fractally Coated Electrodes -- Recording of Monophasic Action Potentials with Fractally Coated Electrodes โ{128}{148} Experimental and Initial Clinical Results -- II Evaluation of Anti- and Proarrhythmic Effects -- Rate Dependence of Antiarrhythmic and Proarrhythmic Properties of Class I and Class III Antiarrhythmic Drugs -- Frequency-Dependent Effects of Class III Antiarrhythmic Agents as Assessed by MAP Recordings โ{128}{148} Possible Advantages of IKs Blockade -- Endothelin-Induced Ventricular Arrhythmias -- III Mechanisms: Atrial and Ventricular Arrhythmias -- The Effects of Atrial Fibrillation on the Monophasic Action Potential of the Caprine Atrium -- Excitable Gap, Antiarrhythmic Actions, Electrical Remodeling: The Role Of MAP Recording in Atrial Fibrillation And Other Atrial Tachyarrhythmias -- Propagated Graded Responses and Dispersion of Repolarization as Two Different Mechanisms of Ventricular Vulnerability to Reentry -- Mechanisms of Induction and Termination of Ventricular Fibrillation -- IV Ischemia โ{128}{148} Dispersion -- Some Effects of Ischaemia and Changes in Ventricular Loading On Repolarisation -- Electrophysiological Characteristics of the M Cell -- Dispersion of Ventricular Repolarization โ{128}{148} Myocardial and Electrocardiographic Markers

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