Title	Intraoperative Irradiation [electronic resource] : Techniques and Results / edited by Leonard L. Gunderson, Christopher G. Willet, Louis B. Harrison, Felipe A. Calvo
Imprint	Totowa, NJ : Humana Press : Imprint: Humana Press, 1999
Connect to	http://dx.doi.org/10.1007/978-1-59259-696-6
Descript	XIX, 551 p. online resource

n Intraoperative Irradiation: Techniques and Results, a team of international radiation oncologists, surgeons, and scientists comprehensively review the techniques, indications, and results of using intraoperative electrons (IOERT) and high-dose rate brachytherapy (HDR-IORT). State-of-the-art topics range from methods and techniques of treatment and issues of normal tissue/organ tolerance to IORT, to techniques and results by disease-site, as well as future possibilities. The disease-site chapters cover every body part for which the potential merit of IORT has been demonstrated, providing a balanced presentation by a radiation oncologist and a surgeon of disease-specific treatment factors. The diseases range from GI cancers to CNS and breast malignancies, and the treatment outcomes discussed include data on disease control (local and distant), on survival (disease-free and overall), and on treatment tolerance. International in authorship and comprehensive in scope, Intraoperative Irradiation: Techniques and Results offers a cutting-edge resource and reference for surgeons, radiation oncologists, physicists, anesthesiologists, medical oncologists, and all others providing IORT and HDR-IORT procedures and cancer care today

I. General Rationale and Historical Perspective -- 1 General Rationale and Historical Perspective of Intraoperative Irradiation -- 2 Biology of Large Dose per Fraction Radiation Therapy -- II. Methods and Techniques of Treatment -- 3 Physical Aspects of Intraoperative Electron-Beam Irradiation -- 4 IOERT Treatment Factors: Technique, Equipment -- 5 Physics of Intraoperative High-Dose-Rate Brachytherapy -- 6 High-Dose-Rate Intraoperative Irradiation (HDR-IORT): Technical Factors -- 7 Intraoperative Irradiation with Electron-Beam or High-Dose-Rate Brachytherapy: Methodological Comparisons -- III. Normal Tissue Toleranceโ{128}{148}IORT -- 8 Normal Tissue Tolerance to Intraoperative Irradiation: The National Cancer Institute Experimental Studies -- 9 Studies at Colorado State University of Normal Tissue Tolerance of Beagles to IOERT, EBRT, or a Combination -- 10 Peripheral Nerve Tolerance: Experimental and Clinical -- IV. Results of IORT with or Without EBRT by Disease Site -- 11 Gastric IORT With or Without EBRT -- 12 IORT in Pancreatic Carcinoma -- 13 Biliary Tract IORT: Bile Duct and Gallbladder -- 14 Primary Colorectal EBRT and IOERT -- 15 Recurrent Colorectal: EBRT With or Without IOERT or HDR-IORT -- 16 HDR-IORT for Colorectal Cancer: Clinical Experience -- 17 Radiation Ablation of Liver Metastases: HDR-IORT With or Without EBRT -- 18 Electron or Orthovoltage IORT for Retroperitoneal Sarcomas -- 19 HDR-IORT for Retroperitoneal Sarcomas -- 20 Extremity and Trunk Soft Tissue Sarcomas: EBRT With or Without IORT -- 21 IORT for Bone Sarcomas -- 22 Locally Advanced Primary and Recurrent Gynecologic Malignancies: EBRT With or Without IOERT or HDR-IORT -- 23 Genitourinary IORT -- 24 Lung Cancer: EBRT With or Without IORT -- 25 Pediatric Malignancies: IORT Alone or With EBRT -- 26 IORT for Head and Neck Cancer -- 27 IORT for CNS Tumors -- 28 IORT for Breast Cancer -- V. Conclusions and Future Possiblities -- 29 Conclusions and Future Possiblitiesโ{128}{148}IORT