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TitleMolecular Biology of Hematopoiesis 6 [electronic resource] / edited by Nader G. Abraham, Antonio Tabilio, Massimo Martelli, Shigetaka Asano, Alberto Donfrancesco
ImprintBoston, MA : Springer US : Imprint: Springer, 1999
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Descript XV, 404 p. online resource


This volume of Molecular Biology of Hematopoiesis is dedicated to many interยญ national scientists and clinicians for their contribution to the field of Hematology/ Oncology presented at the 11th International Symposium on Molecular Biology of Hematopoiesis, which was held in Bormio, Italy, June 25-29, 1998. The continuous support of the Presidents of the meeting, Professor F. Takaku, President of Jichi University, and E. D. Thomas, Nobel Laureate, was greatly acknowledged, especially Professor Takaku, for his vision and support for development of gene therapy in Japan. New information on BMT for autoimmune disease and organ transplantation was presented at the symposium and is published in this volume. Several new findings on gene therapy/transfer into HSC were presented by E. F. Vanin and A. Nienhuis, K. Humphries, 1. A. Nolta, H. E. Heslop, and M. K. Brenner. Professors S. Asano and K. Tani presented new studies on gene transfer into primates. Among the highlights were the new papers on gene transfer presented by G. Wage maker, N. G. Abraham, and M. Onoderea from R. M. BJaese's group. The use of BMT for organ transplant and autoimยญ mune disease was updated and a representative paper is presented in this volume


1. The Development of Hematopoietic Cell Transplantation and Its Application to Organ Transplantation and Autoimmune Diseases -- 2. Hemopoietic Stem Cellsโ{128}{148}Normal and Abnormal -- 3. Immunity and Tolerance are Related, and Governed by Antigen Migration and Localization -- 4. Genetic Approaches to the Investigation of the Mechanisms of Hematopoietic Progenitor Cell Mobilization into the Blood -- 5. Role of Hematopoietic Growth Factors on the Ex Vivo Expansion of Primitive Cord Blood Stem Cells -- 6. Thymus-Independent T Cell Differentiation in Vitro -- 7. Immunogenetics Problems in Cord Blood Transplantation -- 8. Presence of B Cell Progenitors in the Thymus -- 9. De Novo and Secondary AML Cells Differ in their Kinetic Response to HGF Priming -- 10. Molecular Diagnosis of Philadelphia-Positive Leukemias -- 11. Differential Enhancement of Graft-versus-Host (GVH) and Graft-versus- Leukemia (GVL) Reactions by Interleukin-12 (IL-12) -- 12. Expression of C-erb B-2/HER-2 in Patients with Metastatic Breast Cancer Undergoing High-Dose Chemotherapy and Autologous Blood Stem Cell Support -- 13. Clinical Factors Contributing to the Pace of Engraftment after Allogeneic and Autologous Stem Cell Transplantation: Multivariate Analyses -- 14. Clinical Relevance of Bone Marrow Histologic Examination in HIV-Infected Patients -- 15. Molecular Biology of Childhood Solid Tumors: Promises Maintained and Promises Postponed -- 16. Molecular Genetics of Wilms Tumor -- 17. Genetic Heterogeneity in Ewing Tumors and Neuroblastomas -- 18. Mechanisms of Retinoid Inhibition of Cell Proliferation in Neuroblastoma -- 19. High-dose Chemotherapy for Breast Cancer in Europe: From Fashion to Randomization -- 20. Combination of Carboplatin and Etoposide in the Management of Intraocular Retinoblastoma -- 21. Hyper-IL-6 (H-IL-6), a Fusion Protein of Soluble IL-6 Receptor (SIL-6R) and Interleukin-6 (IL-6), Acts Synergistic with Thrombopoietin (TPO) and Stem Cell Factor (SCF) in Expanding Megakaryocyte Progenitors from Human CD34++/CD90+ Cell -- 22. Towards Vaccination with Defined Tumor Antigens? -- 23. Molecular Monitoring of Non-Hodgkinโ{128}{153}s Lymphomas -- 24. Classification of Malignant Lymphomas: State of the Art -- 25. The Pathologic Spectrum of AIDS-Related Non-Hodgkinโ{128}{153}s Lymphomas -- 26. Genesis and Progression of Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma -- 27. Cytokines, Thrombopoietin, and Selectins in Immune Thrombocytopenic Purpura -- 28. Lymphocyte Fractionation in a Magnetic Flow Cell Sorter -- 29. The Basis for a Rational Nutritional Approach to Patients with Cancer -- 30. Differential Expression of IL-3 and GM-CSF Receptor Common Signal Transducing Subunit (?C) during Normal Hematopoietic Differentiation -- 31. Expression of Distal Gatal Transcripts in Erythroid Cells -- 32. Expressions of Fas (CD95) and Fas Ligand in HIV Infected Individuals -- 33. Pattern of PU.1 Binding to M-CSF Receptor Promoter during Monocyte to Macrophage Maturation -- 34. Molecular Biology of Hypoxia-Inducible Factor-1 -- 35. Identification and Characterization of Constituavely Active STAT5 -- 36. An Increase in the Levels of Retroviral-Mediated Transduction of Engrafting Human Hematopoietic Progenitors Can Be Obtained by Manipulation of the Hematopoietic Cell Cycle -- 37. Gene Transfer to the Nervous System Using High-Titer Retroviral Vector -- 38. Hematological Aspects of Common Marmoset Monkey Transplanted with Autologous MDR1 Gene Transduced Peripheral Blood Stem Cells -- 39. Effect of Retrovirus and Adenovirus Mediated Interferon Gene Transfer on Hematopoietic Progenitor Cell Growth -- 40. Prostaglandinโ{128}{153}s Suppressing Effect on Bone Marrow Erythropoiesis in Rats -- 41. Hematological and Biochemical Parameters in Hereditary Spherocytosis under Oxidative Stress -- 42. Lymphocyte Populations in Hereditary Spherocytosis Pre and Post Splenectomy and under Oxidative Stress -- 43. The Hereditary Hemochromatosis Gene and Iron Homeostasis -- 44. Iron and Erythropoiesis: Lessons from Anemic Mice -- 45. Juvenile Hemochromatosis: Search for Candidate Genes -- 46. New Insights on Congenital Dyserithropoietic Anemia Type II -- 47. Iron Chelation in Cancer Therapy -- 48. Transcriptional Regulation of the Ferritin H-Chain and Transferrin Receptor in Hematopoietic Cells

Medicine Cancer research Human genetics Human anatomy Endocrinology Oncology Neurology Medicine & Public Health Oncology Endocrinology Neurology Cancer Research Human Genetics Anatomy


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