Title | Hormonal Carcinogenesis [electronic resource] : Proceedings of the First International Symposium / edited by Jonathan J. Li, Satyabrata Nandi, Sara Antonia Li |
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Imprint | New York, NY : Springer New York, 1992 |
Connect to | http://dx.doi.org/10.1007/978-1-4613-9208-8 |
Descript | XXXIV, 340p. 81 illus. online resource |
Symposium Presentation: Diethylstilbestrol (DES) Syndrome: Present Status of Animal and Human Studies -- 1. Sex Hormones and Carcinogenesis -- Introduction: Androgen Receptors and Regulation of Androgen Action in Normal and Abnormal Cells -- 1 The Conjoint Actions of Androgens and Estrogens in the Induction of Proliferative Lesions in the Rat Prostate -- 2 Enhancement of Prostate Carcinogenesis in Rats by Testosterone and Prolactin -- 3 Hormonal Carcinogenesis in Syrian Hamsters: A Hypothesis Involving Glutathione S-Transferase Regulation -- 2. Hormones, Cell Proliferation, and Carcinogenesis -- Introduction: Current Concepts of Sex Hormone Action (An Overview) -- 4 Control of Uterine Epithelial Growth and Differentiation: Implications for Estrogen-Associated Neoplasia -- 5 A Novel Protein Kinase Activity Identified from Human Breast Cancer Cell Lines -- 6 Estrous Cycle Modification of Rat Mammary Carcinoma Induction -- 7 Hormones, Cell Proliferation, and Mammary Carcinogenesis -- 3. Estrogen Metabolism and Carcinogenicity -- Introduction: Factors Influencing the Metabolism and Action of Estradiol -- 8 Interactions of Carcinogenic Estrogens with Microtubular Proteins -- 9 Differential Interactions of Estradiol Metabolites with the Estrogen Receptor: Genomic Consequences and Tumorigenesis -- 10 Oxidation of Estrogens and Other Steroids by Cytochrome P-450 Enzymes: Relevance to Tumorigenesis -- 11 Metabolism of Moxestrol in the Hamster Kidney: Significance for Estrogen Carcinogenesis -- 4. Hormones and Tumor Promotion -- Introduction: Inhibition of Tumor Promotion by Antihormonal Agents -- 12 Sexual Dimorphism of Hepatic Steroid Metabolism and Its Significance for Chemical Hepatocarcinogenesis -- 13 Growth Stimulation and Tumor Promotion in Rat Liver by Ethynyl Estradiol and Other Estrogens -- 14 Growth Factors in Murine Mammary Adenocarcinomas Induced by Progestins -- 15 The Influence of Steroid Hormones and Antihormones on the Growth and Differentiation of Normal Human Breast Cells in Culture -- 5. Growth Factors and Oncogenes -- Introduction: Molecular Mechanisms of Hormonal Carcinogenesis -- 16 The v-raf and Ha-ras Oncogenes Inhibit Transcription from the Beta-Casein Gene Promoter by Suppression of a Mammary Gland Specific Transcription Factor -- 17 Functional Aspects of EGF-Like Peptides in Ovarian-Steroid Responsive Organs -- 18 Androgen Regulation of Growth Factor and Early Growth Response Gene Expression in Hamster DDT1-MF2 and Human Prostate LNCAP Cells -- 19 Estrogen Regulation of Protooncogene Expression -- 6. Carcinogenesis Risk Assessment of Sex Hormones -- Introduction: Receptor-Mediated Carcinogenesis: Implications for Carcinogenic Risk of Sex Hormones -- 20 Endogenous Estrogen and Progesterone as the Major Determinants of Breast Cancer Risk: Prospects for Control by โNaturalโ and โTechnologicalโ Means -- 21 Synthetic Estrogens and Liver Cancer: Risk Analysis of Animal and Human Data -- 22 Carcinogenic Risk Assessment of Steroid Hormone Exposure in Relation to Prostate Cancer Risk -- Closing Remarks -- Hormonal CarcinogenesisโFuture Perspectives -- Communications -- Cytogenetic Changes in Renal Neoplasms and During Estrogen-Induced Renal Tumorigenesis in Hamsters -- Pituitary Regulation of Sex-Differentiated Promotion of Rat Liver Carcinogenesis -- Modulation of Estrogen Metabolism by Inducers of P-4501A2: Possible Application to the Chemoprevention of Breast Cancer -- Estrogen Metabolism in Subcellular Preparations and Tissue Culture of Syrian Hamster Liver and Kidney -- Hormonal Regulation of Plasminogen Activation in the Human Endometrium -- Your ResearchโOur Lives -- Prostaglandin H Synthase Peroxidase Catalyzed Metabolism of Estrogens in Syrian Hamster and Rabbit Kidney -- Peroxidative Metabolism of Diethylestilbestrol in Ram Seminal Vesicle Cell Cultures: An In-Vitro Model for Studies of Estrogen-Induced Genotoxicity -- In Vivo Effects of Progesterone on Human Breast 17?-Dehydrogenase and Epithelial Cells Mitotic Activities -- DNA Adduct Profiles in Hamster Kidney Following Chronic Exposure to Various Carcinogenic and Noncarcinogenic Estrogens -- Hormone-Dependent Activation of c-Ki-ras in N-Methyl-N-Nitrosourea (MNU)-Induced Mouse Mammary Tumors -- Growth Hormone Regulation of the c-myc Gene During Sex-Differentiated Rat Liver Carcinogenesis -- Fetal Stromal Cells Produce a TGF that Elicits Hyperplasia in Adult Mammary Epithelium -- Induction of Catechol Estrogen Formation by Indole-3-Carbinol -- Cytochrome P-450 Mediated Activation and Irreversible Binding of Tamoxifen to Rat and Human Liver Proteins -- Neonatal Diethylstilbestrol Prevents Spontaneously Developing Mammary Tumors -- Hormone-Dependent Uterine Adenocarcinoma Following Developmental Treatment with Diethylstilbestrol: A Murine Model for Hormonal Carcinogenesis -- Effects of Steroidal and Stilbene Estrogens and Their Peroxidative Metabolites on Microtubular Proteins -- Properties of Micronuclei Induced by Various Estrogens in Two Different Mammalian Cell Systems -- High-Performance Liquid Chromatography Method for the Separation of Potential Metabolites of Estradiol -- Ovarian Hormones Enhance the Carcinogenic Activity of 2,3,7,8-TCDD in Rats