xxvi, 659 pages : color illustrations, charts ; 28 cm
CONTENT
Part I: Genetics, molecular and cellular biology -- 1. Genetics of frontotemporal dementia -- 2. Aging, brain-derived neurotrophic factor (BDNF) and its Val66Met polymorphism: a focus on neuropsychology, the visual system, and brain structures -- 3. Aging, demented patients, and polymorphisms in cytokine genes -- 4. RNA fragments and brain aging -- 5. Centrosome functions and remodeling during neuronal development and centrosome abnormalities in neuronal disorders, disease, and in aging -- 6. Brain aging and microarray analysis -- 7. Human nuclear tau and aging -- 8. Lipoxidation: features, neurological tissues and aging -- 9. Aging modifies concentration and metabolism of amino acids and associated receptor functionality in the brain -- 10. How 3’,5’-cyclic nucleotide phosphodiesterases change in the brain with normal aging and dementia -- 11. The prohibitin complex in aging and neurodegeneration -- 12. Synaptic ATPase and energy metabolism in the nervous system: roles and changes in the aging process -- Part II: Neurological and imaging features -- 13. Microstructural imaging of the human brain with normal and "Abnormal" aging using diffusion magnetic resonance imaging -- 14. Imaging the brain and its vascular in aging: applications of optical coherence tomography angiography -- 15. Potential involvement of perineuronal nets in brain aging: an anatomical point of view -- 16. Grey-matter networks in aging -- 17. Changes in brain synapse-related molecules with age -- 18. Macroautophagy and chaperone-mediated autophagy in aging -- 19. Neuronal L-type calcium channels in aging -- 20. The impact of aged microglia on D-serine-regulated glutamatergic transmission -- 21. Ion channels and the aging brain -- 22. Dendritic spine remodeling and aging -- 23. High-density lipoprotein-cholesterol and neuroaging: memory and gyrification of the insular and frontal opercular cortex -- 24. Astrocyte and microglial aging: morphology and modeling -- 25. Cerebellum - aging of the neuronal machine -- 26. Lipids, beta-secretase 1, and Alzheimer disease -- 27. Aging, myelination and the optic nerve -- 28. Linking proteostasis, aging, and brain ischemia -- 29. Luteinizing hormone and the aging nervous system -- 30. Insights into aging using transcranial magnetic stimulation -- 31. Alpha rhythms: what they are and how they alter with aging -- 32. Nicotine and its derivatives in healthy brain aging -- Part III: Physiological aspects -- 33. Environmental enrichment and physiological aging -- 34. Treadmill exercise and neuroinflammation: links with aging -- 35. Impact of aerobic exercise on brain structure in models of aging: hippocampus and beyond -- 36. The effects of cardiorespiratory fitness on brain and cognitive aging -- 37. Aging, babble noise, and the processing of speech perception -- 38. The blood-brain barrier in aging -- Part IV: Behavior and psychopathological aspects -- 39. Linking aging, anticholinergic drug use, and cognitive impairment -- 40. Cognitive frailty: definitions, components and impact on disability, and mortality -- 41. Cognitive impairment (brain) and (et) dynapenia (D) “BED” in older persons: role of arterial tree -- 42. Disentangling the effects of aging and ovarian hormone loss on sleep: implications for health and disease -- 43. Role of DNA methylation in aging-related cognitive functioning -- 44. Depression in the elderly and psychobiotics -- Part V: Diet and nutrition -- 45. Aging, dietary patterns and cognition -- 46. Geriatric nutritional risk index: applications and limitations -- 47. Diet, inflammation, and neurocognitive aging -- 48. The dietary approaches to stop hypertension (DASH) and Mediterranean-DASH intervention for neurodegenerative delay (MIND) diets and brain aging -- 49. The ketogenic diet and healthy brain aging -- 50. Autophagy and aging: diet, exercise, and the link with the target of rapamycin complex 1 (TORC) -- 51. Dietary flavonoids and brain health in ageing: food for thought -- 52. Antioxidant effects of curcumin and neuroaging -- 53. Lipoic acid and vitamin D3 and their use in preventing brain aging -- 54. Effects of β-hydroxy-β-methyl-butyrate (HMB) supplementation on biomarkers for cognitive function and electrophysiological processes in aging -- 55. Hydration, the brain, and aging