Title | Malignant Brain Tumours [electronic resource] / edited by David G. T. Thomas, David I. Graham |
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Imprint | London : Springer London, 1995 |
Connect to | http://dx.doi.org/10.1007/978-1-4471-1877-0 |
Descript | XXI, 377 p. online resource |
1 Cellular and Molecular Approaches to the Study of Gliomas and Glial Development -- Glial cell development in the rat optic nerve -- Control of self-renewal in the O-2A lineage -- Glial and neuronal development in the retina and cortex -- Ramifications of current development studies for neuropathology -- Potential for positive feedback loops as contributors to growth of gliomas -- Conclusion -- References -- 2 Molecular Genetics of Brain Tumours -- Genetic techniques in studies of brain tumours -- Molecular basis of tumorigenesis -- Molecular genetics of benign brain tumours -- Cytogenetic and molecular genetic studies of malignant brain tumours: gliomas -- Oncogenes and gliomas -- Molecular genetics of neuroblastomas -- Conclusion -- References -- 3 Current Concepts of the Histopathological Classification of Tumours of the Central Nervous System -- Tumours of neuroepithelial tissue -- References -- Colour plate section appears between pages 42 and 43 -- 4 General Introduction to the Clinical Features of Malignant Brain Tumours -- Epidemiology -- Clinical presentation of primary malignant brain tumours -- Specific clinical syndromes -- Glioblastoma -- References -- 5 Complications of Primary Malignant Brain Tumours -- Complications of the tumour itself -- Complications of treatment -- References -- 6 Low-grade Gliomas -- Low-grade cerebral astrocytoma -- Neurosurgical management -- Evaluation of surgical results -- Future Considerations -- Acknowledgements -- References -- 7 Management of Brain Tumours in Childhood -- Introduction: the sites; the cells; the patients -- Primitive neuroectodermal tumour (PNET) -- Brain stem glioma -- Craniopharyngioma -- Ependymoma -- Pineal region tumours -- Conclusion -- References -- 8 Central Nervous System Neoplasms in Acquired Immunodeficiency Syndrome -- Primary CNS lymphoma -- Systemic non-Hodgkinโs lymphoma -- Kaposiโs sarcoma -- Pathogenesis of neoplasms in immune deficiency -- References -- 9 Metastatic Brain Tumours -- General aspects -- Signs and symptoms -- Investigations -- Treatment -- Outcome of treatment -- References -- 10 Diagnostic Imaging of Brain Tumours -- Detection of an abnormality -- Localization and assessment of extent of abnormality -- Characterization of a lesion -- Imaging characteristics of intrinsic tumours -- Facilitation of treatment and further surgical planning -- Monitoring of therapy and outcome of treatment -- References -- 11 Surgery for Primary Malignant Brain Tumours -- Historical introduction -- Principles of surgery -- Principles of perioperative care -- Surgical methods -- Additional surgical methods -- Surgical treatment of gliomas within a specific site -- Recent advances in surgical methods -- Results of surgery -- The case for reoperation for gliomas -- Conclusion -- References -- 12 Radiotherapy for Malignant Brain Tumours -- Biological basis of radiotherapy -- Radiation tolerance of the central nervous system -- Radiotherapy technique -- New radiotherapy techniques -- Radiotherapy in specific tumours -- Radiotherapy in other tumours: optic nerve glioma; meningioma; craniopharyngioma -- Conclusion -- References -- 13 Chemotherapy of Malignant Brain Tumour -- Summary -- Special features of chemotherapy of malignant brain tumours -- Specific treatment -- Clinical classification of malignant CNS neoplasia -- Conclusion -- Appendix I: Some abbreviations and acronyms -- References -- 14 Immunotherapy of Brain Tumours -- Brain tumour immunology: surface antigens on brain tumour; humoral immune response; cell-mediated immune response; modulation of the host immune response by gliomas -- Immunotherapy -- References