Title | Cell and Gene Therapies [electronic resource] / edited by Miguel-Angel Perales, Syed A. Abutalib, Catherine Bollard |
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Imprint | Cham : Springer International Publishing : Imprint: Springer, 2019 |
Edition | 1st ed. 2019 |
Connect to | https://doi.org/10.1007/978-3-319-54368-0 |
Descript | VI, 288 p. 12 illus., 11 illus. in color. online resource |
Historical perspective and current focus -- Part I: Genetically modified T cells (Chimeric antigen receptors and T cell receptors): Chimeric antigen receptor-T cells: Antigen selection, CAR development and future prospects -- Chimeric antigen receptor-T cells for leukemias in children: Methods, data and challenges -- Chimeric antigen receptor-T cells for leukemias in adults- Methods, data and challenges -- Chimeric antigen receptor-T cells for lymphomas: Methods, data and challenges -- T-cell receptors-gene modified T-cells for cancer -- Methods, data and challenges. -- Part II: Beyond chimeric antigen receptor and T-cell receptors - Data, Consensus & Challenges: Cytotoxic T cells for infections: From donor-specific to “off the shelf” -- Donor lymphocyte infusion in different transplant settings: When and how?- T-regulatory cells: Broadening applicability -- Tumor infiltrating lymphocytes: Current concepts and practices -- Part III: Beyond T-cells: Natural killer cells: What have we learned?- Dendritic cells in hematopoietic cell transplantation -- Mesenchymal stem cells: From bench to bedside and back -- Cell Therapies: Regulatory concerns and data collection -- Part IV: Gene Therapy: Gene therapy for hematologic malignancies and in transplant setting -- Gene therapy for nonmalignant disorders -- Future prospects of cell and gene therapies