I: Perspectives -- A historical perspective on scar management -- The global impact of scars -- Medical conditions associated with scarring and fibrosis -- Scars and scar management: ethical considerations -- II: Formation -- Scar histopathology and morphologic classification -- The cellular and molecular basis of scarring: the paradigm of hypertrophic scarring after thermal injury -- The biomechanics of scar formation -- III: Mitigation -- An approach to scar mitigation -- Optimizing wound healing and scar formation -- IV: Rehabilitation -- Medical management of scars -- Neurobiology of scars: managing pain and itch -- Surgical scar revision -- Lasers and light devices in scar management -- Laser-assisted delivery of therapeutic agents -- Fat grafting for scar treatment -- Multimodal scar management -- Atrophic scar management -- Scar management in skin of color -- Rehabilitative burn scar management -- Scar camouflage -- Medical tattooing -- A pediatric perspective -- A perspective from military medicine -- Recovery and reintegration after burn injury -- Integrating scar management into clinical practice -- V: Prevention -- Scar treatment, restoration, and prevention—beyond the horizon? -- Fetal wound healing -- Clinical scar research: quantitative and qualitative assessment of hypertrophic burn scars