I: Cellular physiology -- Principles of cell and membrane function -- Homeostasis: volume and composition of body fluid compartments -- Signal transduction, membrane receptors, second messengers, and regulation of gene expression -- II: The nervous system -- The nervous system: introduction to cells and systems -- Generation and conduction of action potentials -- Synaptic transmission -- The somatosensory system -- The special senses -- Organization of motor function -- Higher functions of the nervous system -- The autonomic nervous system and its central control -- III: Muscle -- Skeletal muscle physiology -- Cardiac muscle -- Smooth muscle -- IV: The cardiovascular system -- Overview of circulation -- Elements of cardiac function -- Properties of the vasculature -- Regulation of the heart and vasculature -- Integrated control of the cardiovascular system -- V: The respiratory system -- Structure and function of the respiratory system -- Static lung and chest wall mechanics -- Dynamic lung and chest wall mechanics -- Ventilation (V.), perfusion (Q.), and V./Q. relationships -- Oxygen and carbon dioxide transport -- Control of respiration -- Nonrespiratory functions of the lung -- VI: Gastrointestinal physiology -- Functional anatomy and general principles of regulation in the gastrointestinal tract -- The cephalic, oral, and esophageal phases of the integrated response to a meal -- The gastric phase of the integrated response to a meal -- The small intestinal phase of the integrated response to a meal -- The colonic phase of the integrated response to a meal -- Transport and metabolic functions of the liver -- VII: The renal system -- Elements of renal function -- Solute and water transport along the nephron: tubular function -- Control of body fluid osmolality and volume -- Potassium, calcium, and phosphate homeostasis -- Role of the kidneys in the regulation of acid-base balance -- VIII: The endocrine and reproductive systems -- Introduction to the endocrine system -- Hormonal regulation of energy metabolism -- Hormonal regulation of calcium and phosphate metabolism -- The hypothalamus and pituitary gland -- The thyroid gland -- The adrenal glands -- The male and female reproductive systems

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