Title | Photosensitive Molecules for Controlling Biological Function [electronic resource] / edited by James J. Chambers, Richard H. Kramer |
---|---|
Imprint | Totowa, NJ : Humana Press, 2011 |
Connect to | http://dx.doi.org/10.1007/978-1-61779-031-7 |
Descript | XIV, 298p. online resource |
Introduction to Part I: Caged Neurotransmitters -- Targeting and Excitation of Photoactivatable Molecules: Design Considerations for Neurophysiology Experiments -- Are Caged Compounds Still Useful? -- Chromophores for the Delivery of Bioactive Molecules with Two-Photon Excitation -- Introduction to Part II: Natural Photosensitive Proteins -- Light-Activated Ion Pumps and Channels for Temporally-Precise Optical Control of Activity in Genetically-Targeted Neurons -- Vertebrate and Invertebrate Rhodopsins: Light Control of G Protein Signaling -- Restoring Visual Function after Photoreceptor Degeneration: Ectopic Expression of Photosensitive Proteins in Retinal Neurons -- Introduction to Part III: Small Molecule Photoswitches -- Photoswitch Design -- Photoswitchable Voltage-Gated Ion Channels -- Optical Manipulation of Protein Activity and Protein Interactions Using Caged Proteins and Optical Switch Protein Conjugates -- Structure-Based Design of Light-Controlled Proteins -- Photoswitchable Ligand-Gated Ion Channels