Title | Mass Spectrometry Imaging [electronic resource] : Principles and Protocols / edited by Stanislav S. Rubakhin, Jonathan V. Sweedler |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2010 |
Connect to | http://dx.doi.org/10.1007/978-1-60761-746-4 |
Descript | XIV, 490 p. online resource |
Introductory Reviews and Tutorials -- Imaging Mass Spectrometry: Viewing the Future -- A Mass Spectrometry Primer for Mass Spectrometry Imaging -- Imaging of Metals, Metalloids, and Non-metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in Biological Tissues -- Protocols for MS Imaging of Distribution of Small Molecules Including Metabolites and Pharmaceuticals -- Lipid Detection, Identification, and Imaging Single Cells with SIMS -- The Application and Potential of Ion Mobility Mass Spectrometry in Imaging MS with a Focus on Lipids -- Quantitative Imaging of Chemical Composition in Single Cells by Secondary Ion Mass Spectrometry: Cisplatin Affects Calcium Stores in Renal Epithelial Cells -- Imaging MALDI Mass Spectrometry of Sphingolipids Using an Oscillating Capillary Nebulizer Matrix Application System -- Mapping Pharmaceuticals in Rat Brain Sections Using MALDI Imaging Mass Spectrometry -- Laser Ablation Electrospray Ionization for Atmospheric Pressure Molecular Imaging Mass Spectrometry -- Matrix-Assisted Laser Desorption/Ionization and Nanoparticle-Based Imaging Mass Spectrometry for Small Metabolites: A Practical Protocol -- Cellular Imaging Using Matrix-Enhanced and Metal-Assisted SIMS -- Tandem Mass Spectrometric Methods for Phospholipid Analysis from Brain Tissue -- Chemical Imaging with Desorption Electrospray Ionization Mass Spectrometry -- Mass Spectrometry Imaging of Small Molecules Using Matrix-Enhanced Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (ME-SALDI-MS) -- Preparation of Single Cells for Imaging Mass Spectrometry -- Applying Imaging ToF-SIMS and PCA in Differentiation of Tissue Types -- Protocols for MS Imaging of Distribution of Peptides and Proteins -- Direct Molecular Analysis of Whole-Body Animal Tissue Sections by MALDI Imaging Mass Spectrometry -- MALDI Direct Analysis and Imaging of Frozen Versus FFPE Tissues: What Strategy for Which Sample? -- On Tissue Protein Identification Improvement by N-Terminal Peptide Derivatization -- Specific MALDI-MSI: TAG-MASS -- Structurally Selective Imaging Mass Spectrometry by Imaging Ion Mobility-Mass Spectrometry -- Tutorial: Multivariate Statistical Treatment of Imaging Data for Clinical Biomarker Discovery -- Applications of MALDI-MSI to Pharmaceutical Research -- Tissue Preparation for the In Situ MALDI MS Imaging of Proteins, Lipids, and Small Molecules at Cellular Resolution -- Imaging of Similar Mass Neuropeptides in Neuronal Tissue by Enhanced Resolution MALDI MS with an Ion Trap – OrbitrapTM Hybrid Instrument -- Mass Spectrometric Imaging of Neuropeptides in Decapod Crustacean Neuronal Tissues -- Mass Spectrometry Imaging Using the Stretched Sample Approach