Title | Analgesia [electronic resource] : Methods and Protocols / edited by Arpad Szallasi |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2010 |
Connect to | http://dx.doi.org/10.1007/978-1-60327-323-7 |
Descript | XVIII, 560 p. 97 illus., 4 illus. in color. online resource |
Alternatives to Mammalian Pain Models 1: Use of C. elegans for the Study of Volatile Anesthetics -- Alternatives to Mammalian Pain Models 2: Using Drosophila to Identify Novel Genes Involved in Nociception -- Animal Models of Acute Surgical Pain -- Animal Models of Acute and Chronic Inflammatory and Nociceptive Pain -- Noxious Heat Threshold Measured with Slowly Increasing Temperatures: Novel Rat Thermal Hyperalgesia Models -- Locomotor Activity in a Novel Environment as a Test of Inflammatory Pain in Rats -- Rationale and Methods for Assessment of Pain-Depressed Behavior in Preclinical Assays of Pain and Analgesia -- Animal Models of Orofacial Pain -- Migraine Models -- Experimental Models of Visceral Pain -- Human Correlates of Animal Models of Chronic Pain -- Human Experimental Pain Models 1: The Ultraviolet Light UV-B Pain Model -- Human Experimental Pain Models 2: The Cold Pressor Model -- Human Experimental Pain Models 3: Heat/Capsaicin Sensitization and Intradermal Capsaicin Models -- The Value of the Dental Impaction Pain Model in Drug Development -- Live Cell Imaging for Studying G Protein-Coupled Receptor Activation in Single Cells -- Recombinant Cell Lines Stably Expressing Functional Ion Channels -- Ion Channels in Analgesia Research -- Electrophysiological and Neurochemical Techniques to Investigate Sensory Neurons in Analgesia Research -- The Genetics of Pain and Analgesia in Laboratory Animals -- RT-PCR Analysis of Pain Genes: Use of Gel-Based RT-PCR for Studying Induced and Tissue-Enriched Gene Expression -- Gene-Based Approaches in the Study of Pathological Pain -- Linkage Analysis and Functional Evaluation of Inherited Clinical Pain Conditions -- Rat Bone Marrow Stromal Cells and Oligonucleotides in Pain Research -- Transplantation of Human Mesenchymal Stem Cells in the Study of Neuropathic Pain -- Delivery of RNA Interference to Peripheral Neurons In Vivo Using Herpes Simplex Virus -- Combination of Cell Culture Assays and Knockout Mouse Analyses for the Study of Opioid Partial Agonism -- Assessing Potential Functionality of Catechol-O-methyltransferase (COMT) Polymorphisms Associated with Pain Sensitivity and Temporomandibular Joint Disorders -- Genetic Polymorphisms and Human Sensitivity to Opioid Analgesics -- Molecular Assays for Characterization of Alternatively Spliced Isoforms of the Mu Opioid Receptor (MOR) -- Inhalational Anesthetic Photolabeling -- Measuring Membrane Protein Interactions Using Optical Biosensors -- Proteomics and Metabolomics and Their Application to Analgesia Research -- Preemptive Analgesia: Problems with Assessment of Clinical Significance -- Standardization of Pain Measurements in Clinical Trials -- Procedural Sedation and Analgesia Research -- Non-invasive Transcranial Direct Current Stimulation for the Study and Treatment of Neuropathic Pain -- Pain Imaging in the Emerging Era of Molecular Medicine -- Current and Emerging Pharmacologic Therapies for Pain and Challenges Which Still Lay Ahead