Office of Academic Resources
Chulalongkorn University
Chulalongkorn University

Home / Help

TitleEssential Concepts in Toxicogenomics [electronic resource]
Author edited by Donna L. Mendrick, William B. Mattes
ImprintTotowa, NJ : Humana Press, 2008
Connect tohttp://dx.doi.org/10.1007/978-1-60327-048-9
Descript XI, 277 p. online resource

SUMMARY

The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field


CONTENT

Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity -- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology -- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications -- Role of Statistics in Toxicogenomics -- Predictive Toxicogenomics in Preclinical Discovery -- In Vivo Predictive Toxicogenomics -- Bioinformatics: Databasing and Gene Annotation -- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics -- Toxicogenomics in Biomarker Discovery -- From Pharmacogenomics to Translational Biomarkers -- Public Consortium Efforts in Toxicogenomics -- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations


Medicine Human genetics Pharmacology Bioinformatics Biomedicine Human Genetics Pharmacology/Toxicology Bioinformatics



Location



Office of Academic Resources, Chulalongkorn University, Phayathai Rd. Pathumwan Bangkok 10330 Thailand

Contact Us

Tel. 0-2218-2929,
0-2218-2927 (Library Service)
0-2218-2903 (Administrative Division)
Fax. 0-2215-3617, 0-2218-2907

Social Network

  line

facebook   instragram