Title | Electroporation Protocols [electronic resource] : Preclinical and Clinical Gene Medicine / edited by Shulin Li |
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Imprint | Totowa, NJ : Humana Press, 2008 |
Connect to | http://dx.doi.org/10.1007/978-1-59745-194-9 |
Descript | XXII, 524 p. 142 illus., 1 illus. in color. online resource |
Basic Concepts of DNA Transfer via Electroporation -- Application of Electroporation Gene Therapy: Past, Current, and Future -- Mechanism by Which Electroporation Mediates DNA Migration and Entry into Cells and Targeted Tissues -- Applicator and Electrode Design for In Vivo DNA Delivery by Electroporation -- Electrode Assemblies Used for Electroporation of Cultured Cells -- Formulations for DNA Delivery via Electroporation In Vivo -- Overview of Drug Delivery and Alternative Methods to Electroporation -- Nanoelectroporation: A First Look -- In Vitro Targeted Gene Delivery via Electroporation -- Nucleofection of Human Embryonic Stem Cells -- Delivery of Whole Tumor Lysate into Dendritic Cells for Cancer Vaccination -- Delivery of Tumor-Antigen-Encoding mRNA into Dendritic Cells for Vaccination -- Delivery of DNA into Natural Killer Cells for Immunotherapy -- Electroporation of Adherent Cells In Situ for the Study of Signal Transduction and Gap Junctional Communication -- Delivery of DNA into Adipocytes within Adipose Tissue -- In Vivo Targeted Gene Delivery via Electroporation -- Delivery of DNA into Muscle for Treating Systemic Diseases: Advantages and Challenges -- Delivery of DNA into Skeletal Muscle in Large Animals -- Delivery of DNA into Skin via Electroporation -- Electroporation-Mediated Gene Delivery to the Lungs -- Delivery of DNA into Bladder via Electroporation -- Analysis of Gene Function in the Retina -- Optical In Vivo Imaging of Electrically Mediated Delivery of siRNA into Muscle for Gene Function Analysis -- Electroporation of Adult Zebrafish -- Treatment of Cancer via Electroporation Gene Therapy -- Flow Electroporation with Pulsed Electric Fields for Purging Tumor Cells -- Delivery of DNA into Tumors -- Intratumoral Bleomycin and IL-12 Electrochemogenetherapy for Treating Head and Neck Tumors in Dogs -- Systemic IL-12 Gene Therapy for Treating Malignancy via Intramuscular Electroporation -- Treatment of SCCVII Tumors with Systemic Chemotherapy and Interleukin-12 Gene Therapy Combination -- Electroporation for Drug and Gene Delivery in the Clinic: Doctors Go Electric -- IL-2 Plasmid Electroporation: From Preclinical Studies to Phase I Clinical Trial -- Treatment of Other Diseases via Electroporation Gene Therapy -- Factor IX Gene Therapy for Hemophilia -- KGF-1 for Wound Healing in Animal Models -- Hepatocyte Growth Factor Gene Therapy for Hypertension -- Electroporation of Corrective Nucleic Acids (CNA) In Vivo to Promote Gene Correction in Dystrophic Muscle -- Gene Delivery to Dystrophic Muscle -- Effect of Electroporation on Cardiac Electrophysiology -- Muscle and Fat Mass Modulation in Different Clinical Models -- Applications of Electroporation for DNA Vaccination -- DNA Vaccination for Prostate Cancer -- HER2/neu DNA Vaccination for Breast Tumors -- Electroporation-Mediated HBV DNA Vaccination in Primate Models -- Taking Electroporation-Based Delivery of DNA Vaccination into Humans: A Generic Clinical Protocol -- Production of Monoclonal Antibody by DNA Immunization with Electroporation