Title | Cardiac Gene Therapy [electronic resource] : Methods and Protocols / edited by Kiyotake Ishikawa |
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Imprint | New York, NY : Springer New York : Imprint: Humana Press, 2017 |
Connect to | http://dx.doi.org/10.1007/978-1-4939-6588-5 |
Descript | XI, 355 p. 93 illus., 78 illus. in color. online resource |
Current Methods in Cardiac Gene Therapy: Overview -- Silencing Genes in the Heart -- Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs -- Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro -- Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction -- Production and Characterization of Vectors Based on the Cardiotropic AAV Serotype 9 -- Cell-Based Measurement of Neutralizing Antibodies Against Adeno-Associated Virus (AAV) -- Synthesis of Modified mRNA for Myocardial Delivery -- Exosomes-Based Gene Therapy for MicroRNA Delivery -- Lipidoid mRNA Nanoparticles for Myocardial Delivery in Rodents -- Gene Transfer in Isolated Adult Cardiomyocytes -- Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells -- Gene Transfer to Rodent Hearts In Vivo -- Ultrasound-Targeted Microbubble Destruction for Cardiac Gene Delivery -- A Needleless Liquid Jet Injection Delivery Approach for Cardiac Gene Therapy -- Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques -- Direct Myocardial Injection of Vectors -- Selective Pressure-Regulate Retroinfusion for Gene Therapy Application in Ischemic Heart Disease -- Cardiac Gene Delivery Using Recirculating Devices -- Molecular Cardiac Surgery with Recirculating Delivery (MCARD): Procedure and Vector Transfer -- Gene Delivery for the Generation of Bioartificial Pacemaker -- Gene Therapy for Post-Infarction Ventricular Tachycardia -- MicroRNA Delivery Strategies to the Lung in a Model of Pulmonary Hypertension -- Inhaled Gene Transfer for Pulmonary Circulation