Title | Data Mining Techniques for the Life Sciences [electronic resource] / edited by Oliviero Carugo, Frank Eisenhaber |
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Imprint | New York, NY : Springer New York : Imprint: Humana Press, 2016 |
Edition | 2nd ed. 2016 |
Connect to | http://dx.doi.org/10.1007/978-1-4939-3572-7 |
Descript | XIII, 552 p. 97 illus., 84 illus. in color. online resource |
Update on Genomic Databases and Resources at the National Center for Biotechnology Information -- Protein Structure Databases -- The MIntAct Project and Molecular Interaction Databases -- Applications of Protein Thermodynamic Database for Understanding Protein Mutant Stability and Designing Stable Mutants -- Classification and Exploration of 3D Protein Domain Interactions using Kbdock -- Data Mining of Macromolecular Structures -- Criteria to Extract High Quality Protein Data Bank Subsets for Structure Users -- Homology-based Annotation of Large Protein Datasets -- Identification and Correction Of Erroneous Protein Sequences in Public Databases -- Improving the Accuracy of Fitted Atomic Models in Cryo-EM Density Maps Of Protein Assemblies Using Evolutionary Information From Aligned Homologous Proteins -- Systematic Exploration of an Efficient Amino Acid Substitution Matrix, MIQS -- Promises and Pitfalls of High Throughput Biological Assays -- Optimizing RNA-seq Mapping with STAR -- Predicting Conformational Disorder -- Classification of Protein Kinases Influenced By Conservation of Substrate Binding Residues -- Spectral-Statistical Approach for Revealing Latent Regular Structures in DNA Sequence -- Protein Crystallizability -- Analysis and Visualization of ChIP-Seq and RNA-Seq Sequence Alignments using ngs.plot -- Data Mining with ontologies -- Functional Analysis of Metabolomics Data -- Bacterial Genomics Data Analysis in the Next-Generation Sequencing Era -- A Broad Overview of Computational Methods for Predicting the Pathophysiological Effects of Non-Synonymous Variants -- Recommendation Techniques for Drug-Target Interaction Prediction and Drug-Repositioning -- Protein Residue Contacts and Prediction Methods -- The Recipe for Protein Sequence-Based Function Prediction and its Implementation in the Annotator Software Environment -- Big Data, Evolution, and Metagenomes: Predicting Disease from Gut Microbiota Codon Usage Profiles -- Big Data in Plant Science: Resources and Data Mining Tools for Plant Genomics and Proteomics.