Welfare Aspects of Transgenic Animals [electronic resource] : Proceedings EC-Workshop of October 30, 1995 / edited by L. F. M. Van Zutphen, M. Van Der Meer
Imprint
Berlin, Heidelberg : Springer Berlin Heidelberg, 1997
The quality of animal models used in biomedical research has increased substantially since the first successful microinjections of foreign DNA fragments into a mouse zygote in the early 1980s. New well-defined animal models developed either by microinjection techniques or by homologous recombination in embryonic stem (ES) cells, have become widely available and several classical animal models have now been replaced by these transgenic models. Transgenic animals also fulfill increasingly important roles in other fields, like livestock production or in biopharming. In the framework of the European Commission's Biotechnology Programme, a workshop has been organized at Utrecht University (30 October, 1995) with leading experts in the field of animal transgenesis and animal welfare as presenting authors. This book summarizes the papers presented at the workshop
CONTENT
Scientific applications of transgenic mouse models -- of defined mutations into the mouse germline -- Growth hormone overproduction in transgenic mice: Phenotypic alterations and deduced animal models -- Prospectives of transgenic animals for the pharmaceutical industry -- Assessing the welfare of transgenic animals -- Production of transgenic animals: Practical problems and welfare aspects -- Use of transgenic animals and welfare implications -- Transgenic animals: the need for ethical dialogue -- Legislation on transgenic animals in Europe -- The Utrecht workshop on welfare aspects of transgenic animals: General discussion -- Annex: list of participants
