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TitleFrom Hypertension to Heart Failure [electronic resource] / edited by Michael Bรถhm, John H. Laragh, Manfred Zehender
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1998
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Descript XIII, 258p. 37 illus. online resource


Arterial hypertension, coronary heart disease and heart failยญ ure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become inยญ creasingly clear that they are closely and causally interrelated and that their relationship can have a significant bearing on prognosis. Epidemiological studies have shown that arterial hypertension is one of the most important risk factors for deยญ veloping heart failure. Only one in four patients with hyperยญ tension is adequately managed, and in 50% of cases, the hypertension has not been recognised or treated. Patients with pre-existing hypertension who go on to suffer an acute myocardial infarction have usually not previously had typiยญ cal angina symptoms, the infarct territory is larger, life threatening arrhythmias are commoner and hence in-hospiยญ tal mortality and long-term prognosis are markedly worse. The presence of raised blood pressure in the post-infarct phase doubles the risk of manifest heart failure. The close relationship between hypertension, coronary heart disease and heart failure makes the choice of therapeuยญ tic strategy particularly important. Agents and classes of agents that have prognostic value in all three conditions should be considered first, as synergy might result in addiยญ tional benefits. In such patients, this sort of therapeutic deciยญ sion-making might have further advantages. The use of these agents may prevent complications which are not yet clinically obvious (such as heart failure)


I Introduction -- 1 Epidemiologic Insights into Progression from Hypertension to Heart Failure -- II Hypertension -- 2 ?-Blockers in the Treatment of Hypertension: Focus on Carvedilol -- 3 Ergometry in the Assessment of Arterial Hypertension and Antihypertensive Therapy -- III Angina Pectoris -- 4 ?-Adrenergic Antagonists in the Management of Acute Myocardial Infarction -- 5 ?-Blocking Therapy in Patients with Unstable Angina -- 6 Usefulness of ?-Blockers in Sudden Cardiac Death -- 7 ?-Blocking Agents in Patients with Coronary Artery Disease and Myocardial Infarction -- IV Heart Failure -- 8 Molecular Organization of the ?-Adrenergic System -- 9 ?-Adrenergic Signal Transduction Defects in Heart Failure -- 10 ?-Blocker Treatment of Chronic Heart Failure -- 11 Heart Failure: Treatment with ?-Adrenoceptor Antagonists -- V Case Reports -- 12 ?-Receptor Blocker Therapy in Dilated Cardiomyopathy After Doxorubicine Therapy -- 13 ?-Blocker Therapy in Severe Cardiac Heart Failure

Medicine Cardiology Medicine & Public Health Cardiology


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