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TitleTrends in Contrast Media [electronic resource] / edited by Henrick S. Thomsen, Robert N. Muller, Robert F. Mattrey
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1999
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Descript XI, 483 p. online resource


The use of contrast media is required in many applications of modern diagnostic imaging, regardless of which modality is employed. This book aims to provide a different approach to contrast media, which are discussed essentially from the point of view of the radiologist. However, the referring physician will also derive much valuable information from the volume, in that it is elucidated to which contrast media particular groups of patients may be exposed, and the possible consequences of such exposure. Comprehensive sections are devoted to iodinated contrast media and to the contrast media employed in magnetic resonance imaging and ultrasonography. The latest agents to become available receive due attention, and adverse reactions are also covered in detail. A final section considers the use of contrast media in nuclear medicine


I Iodinated Contrast Media -- 1 History of Iodinated Contrast Media -- 2 Design of X-ray Contrast Agents -- 3 Biological Variation, Reproducibility, and Predictability of Experimental Research in Animals -- 4 Experimental Testing of Iodinated Contrast Media Before Human Testing -- 5 Phase I, II, III, and IV Studies: Good Clinical Practice -- 6 Currently Available Iodinated Contrast Media -- 7 Clinical Doses of Contrast Media -- 8 Determination of Glomerular Filtration Rate with Contrast Media -- 9 Neurotoxicity -- 10 Nephrotoxicity -- 11 Adverse Reactions to Iodinated Radiographic Contrast Media -- 12 Treatment of Adverse Reactions -- 13 Hepatic Agents -- 14 Lymphatic Agents -- II Magnetic Resonance Contrast Media -- 15 Chemical Synthesis of Paramagnetic Complexes -- 16 Preparation and Structure-Activity Relationships of Particulate Magnetic Agents -- 17 Magnetic Resonance Contrast Agents of Increased Specificity -- 18 Central Nervous System -- 19 Liver and Pancreas -- 20 Heart -- 21 Kidneys and Adrenal Glands -- 22 The Musculoskeletal System -- 23 Contrast-Enhanced Magnetic Resonance Angiography -- 24 Dynamic Contrast-Enchanced Magnetic Resonance Imaging and Image Processing -- III Ultrasound Contrast Media -- 25 Ultrasound Contrast Media: Past, Present, and Future -- 26 Interaction of Ultrasound and Contrast Agents -- 27 Contrast-Specific Instrumentation and Its Potential Applications -- 28 Bubble Destruction -- 29 Potential for Quantification -- 30 The Vascular Space -- 31 Tumor Imaging with Ultrasound Contrast -- 32 Tissue Perfusion and Enhancement on Gray-scale -- 33 Cardiac Applications -- 34 Targeting and Delivery of Drugs with Ultrasound Contrast Agents -- 35 Can the Presence of Contrast Media Promote Ultrasound Bioeffects? -- IV Radiopharmaceuticals (Nuclear Medicine) -- 36 Imaging Techniques and Existing Agents -- 37 New and Future Trends in Radiopharmaceuticals -- List of Contributors

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