TitlePlatelets and Atherosclerosis [electronic resource] / edited by Christof Kessler
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1991
Connect tohttp://dx.doi.org/10.1007/978-3-642-58225-7
Descript XII, 110 p. 30 illus. online resource

SUMMARY

Most patients with cerebrovascular diseases are treated with antiplatelet drugs. Basic thromosis research showed that platelets are an important factor in the pathogenesis of ar- therosclerosis and its complications, but other compounds as macrophages and vessel wall factors are also involved in this process. The aim of this volume is to connect labora- tory findings with clinical applications


CONTENT

The Role of Platelets in the Early Stages of Atherosclerosis -- Proliferation of Vascular Smooth Muscle Cells in the Absence of Platelets. In Vivo Study in Deendothelialized Carotid Arteries of Thrombocytopenic Rats -- The Role of Macrophages in Atherogenesis โ Platelet/Monocyte Interactions -- Animal Models Evaluating Platelet-Modifying Drugs -- Preventive Measures to Reduce Injured Vessel Wall Thrombogenicity -- Interactions Between Platelets in Whole Blood and a Thrombogenic Subendothelial Matrix: Acetylsalicylic Acid and Dipyridamole Inhibit Thrombus Formation Ex Vivo in Human Volunteers -- Human Endothelial Cells Modulate Thrombus Formation in an In Vitro Model of Platelet-Vessel Wall Interactions -- Cerebral Vasocontraction Induced by Thrombin-Stimulated Washed Human Platelets โ A New In Vitro Model to Study Cerebral Vasospasm -- Radioisotopic Monitoring of the Main Mechanisms Involved in Human Atherogenesis -- Modification of Platelet Prosthetic Interaction by Endothelial Cells -- Quantitation of Platelet Thrombus in Cardiac Valve Prostheses with the Radiolabeled Platelets -- 99mTc-HMPAO Thrombocytes: In Vitro Comparison with 111In-Oxine Thrombocytes and Preliminary Clinical Experience -- Thrombogenesis and Antithrombotic Agents in an In Vivo Model for Minimal Endothelial Damage -- Indium-III Platelet Scintigraphy in Stroke Patients


SUBJECT

  1. Medicine
  2. Pharmacology
  3. Nuclear medicine
  4. Cardiology
  5. Neurology
  6. Medicine & Public Health
  7. Neurology
  8. Pharmacology/Toxicology
  9. Nuclear Medicine
  10. Cardiology