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AuthorKmieฤ{135}, Zbigniew. author
TitleCooperation of Liver Cells in Health and Disease [electronic resource] / by Zbigniew Kmieฤ{135}
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2001
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Descript XIII, 151 p. 18 illus. online resource


The book is the first monograph that describes the importance of the interactions between hepatocytes and nonparenchymal liver cells for the functions of both normal and diseased liver. The concise description of major types of non-hepatocytes (sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes) has been followed by the presentation of the role of cellular cross-talks for the physiological regulation of specific liver functions such as uptake and storage of vitamin A, modulation of glucose homeostasis, sinusoidal blood flow regulation, synthesis of eicosanoids, nitric oxide, and growth factors. The functioning of complicated intercellular networks during the course of endotoxin-induced liver damage, and development of liver fibrosis has also been presented


1 Introduction โ{128}{148} Morphology of the Liver Lobule -- 2 Hepatocytes -- 3 Sinusoidal Endothelial Cells -- 4 Kupffer Cells -- 5 Hepatic Stellate Cells -- 6 Pit Cells and Other Intrahepatic Lymphocytes -- 7 Cooperation of Liver Cells in the Synthesis and Degradation of Eicosanoids -- 8 Nitric Oxide as a Mediator of Intercellular Communication in the Liver -- 9 Cooperation of Hepatocytes and Stellate Cells in the Metabolism and Storage of Retinoids -- 10 Cooperation of Liver Cells in the Regulation of Glucose Metabolism -- 11 Cooperation of Liver Cells in the Synthesis of Growth Factors and Respective Binding Proteins -- 12 Cooperation of Liver Cells in the Regulation of Sinusoidal Contractility -- 13 Cross-Talk of Liver Cells in Response to Endotoxin -- 14 Cooperation of Liver Cells in the Process of Liver Fibrosis -- 15 Perspectives -- 16 Summary -- References

Life sciences Human physiology Hepatology Cell biology Life Sciences Life Sciences general Human Physiology Cell Biology Hepatology


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