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TitleThe Skin and Gene Therapy [electronic resource] / edited by Ulrich R. Hengge, Beatrix Volc-Platzer
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2001
Connect tohttp://dx.doi.org/10.1007/978-3-642-56441-3
Descript XIX, 301 p. online resource

CONTENT

Basic Aspects -- 1 The Epidermal Barrier and Strategies for Surmounting It: An Overview -- 2 Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy -- 3 Relevant Animal Models for Skin Gene Therapy -- 4 Nonviral Gene Transfer into the Skin -- 5 Safety and Pharmacokinetics of Naked Plasmid DNA: Studies on Dissemination and Ectopic Expression -- 6 Uptake of DNA by Keratinocytes -- Treatment of Skin Diseases -- Gene Therapy of Inherited Skin Diseases -- Gene Transfer Strategies in Tissue Repair -- Systemic Effects of Skin Gene Therapy -- The Use of Skin-Directed Gene Therapy in the Treatment of Systemic Diseases -- Keratinocyte Gene Therapy Using Cytokine Genes -- Genetic Vaccination Using the Skin -- Principles of Genetic Immunization -- Systematic Modulation of Immune Responses by CpG DNA -- Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma -- Molecular Strategies Interfering with Tumor Progression of Melanoma and Improving Anti-Tumor Immunity -- Prophylactic and Therapeutic DNA Vaccines Against Infectious Diseases


Medicine Immunology Molecular biology Dermatology Oncology Medicine & Public Health Dermatology Immunology Oncology Molecular Medicine



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