Author	McKinley, Michael J. author
Title	The Sensory Circumventricular Organs of the Mammalian Brain [electronic resource] : Subfornical Organ, OVLT and Area Postrema / by Michael J. McKinley, Robin M. McAllen, Pamela Davern, Michelle E. Giles, Jenny Penschow, Nana Sunn, Aaron Uschakov, Brian J. Oldfield
Imprint	Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2003
Connect to	http://dx.doi.org/10.1007/978-3-642-55532-9
Descript	XII, 127p. 28 illus., 3 illus. in color. online resource

The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the brain in which neurons are exposed to the chemical environment of the systemic circulation. Therefore they are ideally placed to monitor the changes in osmotic, ionic and hormonal composition of the blood. This book describes their - General structure and relationship to the cerebral ventricles - Regional subdivisions - Vasculature and barrier properties - Neurons, glia and ependymal cells - Receptors, neurotransmitters, neuropeptides and enzymes - Neuroanatomical connections - Functions

1 Introduction -- 2 Location, General Structure and Ependymal Cells of Sensory Circumventricular Organs -- 2.1 Subfornical Organ -- 2.2 OVLT -- 2.3 Area Postrema -- 3 Regional Subdivisions Within Sensory Circumventricular Organs -- 3.1 Subfornical Organ -- 3.2 OVLT -- 3.3 Area Postrema -- 4 Vasculature, Compartmental Barriers, Neurons and Glia in the Sensory Circumventricular Organs -- 4.1 Subfornical Organ -- 4.2 OVLT -- 4.3 Area Postrema -- 5 Neurochemical Aspects of Sensory Circumventricular Organs -- 5.1 Receptors -- 5.2 Neurotransmitters, Neuropeptides, Hormones and Enzymes -- 6 The Neural Connections of the Sensory Circumventricular Organs -- 6.1 Subfornical Organ -- 6.2 Neural Connections of the OVLT -- 6.3 Area Postrema -- 7 Immediate-Early Gene Expression in Sensory Circumventricular Organs -- 7.1 Angiotensin II -- 7.2 Baroreceptor Activation -- 7.3 Carbachol -- 7.4 Anorectic Peptides - Cholecystokinin, GLP-1 and Amylin -- 7.5 Hypertonicity -- 7.6 Lipopolysaccharide (Endotoxin) -- 7.7 Relaxin -- 7.8 Vomiting and Emetic Stimuli -- 8 Functions of the Sensory Circumventricular Organs -- 8.1 Osmoregulation -- 8.2 Central Actions of Circulating Angiotensin -- 8.3 Influences on Arterial Pressure -- 8.4 Area Postrema and Vomiting -- 8.5 Neuroimmune Responses and Fever -- 8.6 Concluding Remarks