Title | Statistical Methods in Toxicology [electronic resource] : Proceedings of a Workshop during EUROTOX '90 Leipzig, Germany, September 12-14, 1990 / edited by Ludwig Hothorn |
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Imprint | Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1991 |
Connect to | http://dx.doi.org/10.1007/978-3-642-48736-1 |
Descript | IV, 161 p. online resource |
Modern statistical methods in toxicology โ an overview -- Biostatistical analysis of mutagenicity assays -- Statistical analysis of the Ames assay -- Statistical analysis of the micronucleus test with the Fisher-Pitman permutation test -- A statistical analysis of HGPRT-test data by means of computer simulations -- Measuring intra-assay agreement for the Ames salmonella assay -- Tabular overview of statistical methods proposed for the analysis of Ames Salmonella assay data -- Biostatistical analysis of long-term carcinogenicity studies -- Analyses of longterm carcinogenicity studies -- Mathematical models for the initiating and promotive action of carcinogens -- Statistical problems in estimating a threshold in a dose-response model -- Biostatistical analysis of embryo-toxicity studies -- Per-litter analyses for studies in developmental toxicity -- Biometrical analysis of strain differences and litter effects, a case study -- Statistical evaluation of offspring parameters in embryotoxicity studies -- General principles in biostatistical analysis of toxicological studies -- General statistical principles in testing of toxicological studies -- Determination of endpoints in acute and chronic toxicity tests by using generalized linear models -- The need of software validation in routine toxicology -- An application of mixed model ANOVA for the assessment of motor activity in rat behavioural toxocity studies -- Sponsors