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TitleNimodipine [electronic resource] : Pharmacological and Clinical Results in Cerebral Ischemia / edited by Alexander Scriabine, G. M. Teasdale, Dieter Tettenborn, Wise Young
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1991
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Descript XIV, 277p. 50 illus. online resource


Session I. Pharmacology -- Pharmacology Overview: Nimodipine in CNS-Indications -- Changes in Intracellular Free Calcium During Cerebral Ischemia and the Effects of Nimodipine on Calcium and Histological Damage -- Experimental Models of Focal Ischemia: Results with Nimodipine -- The Effect of Nimodipine Pretreatment on Focal Cerebral Ischemia in the Hypertensive Rat -- Cardiac Arrest, Stroke, Subarachnoid Hemorrhage, and Severe Head Injury: What do They Have in Common? -- Dihydropyridines Attenuate Slow Excitatory Amino Acid Neurotoxicity -- Session II. Subarachnoid Hemorrhage -- The Pathophysiology of Arterial Narrowing and Delayed Ischemic Deficit After Subarachnoid Hemorrhage -- Advances in the Diagnosis and Treatment of Aneurysmal Subarachnoid Hemorrhage -- Reviews of Trials on the Effect of Oral Nimodipine on Cerebral Infarction and Outcome Following Subarachnoid Haemorrhage -- Treatment by Nimodipine of Ischemic Neurologic Deficits Due to Vasospasm -- Safety Profile of Nimodipine in Patients with Subarachnoid Hemorrhage -- Session III. Acute Ischemic Stroke -- Pathophysiology of Ischemic Brain Disease -- Positron Emission Tomography in Nimodipine-Treated Patients with Acute Ischemic Stroke -- Brain Regional Pharmacokinetics of 11C-Nimodipine in Patients with Acute Stroke: A Preliminary Account of a Positron Emission Tomographic Study -- Nimodipine and Other Calcium Antagonists in Acute Ischemic Stroke -- Pool Analysis of the European Studies of Nimodipine in Acute Ischemic Stroke -- Session IV. Cerebral Resuscitation -- Pharmacokinetics of Nimodipine in the Dog Resuscitated After Cardiopulmonary Arrest -- Plasma Concentrations of Nimodipine in Patients Resuscitated After an Out-of-Hospital Cardiac Arrest -- Influence of Nimodipine on Cerebral Blood Flow After Cardiac Arrest in Humans -- Early Effects of Nimodipine on Intracranial and Cerebral Perfusion Pressures in Cerebral Anoxia After Out-of-Hospital Cardiac Arrest -- Nimodipine in Out-of Hospital Ventricular Fibrillation: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial -- Session V. Severe Head Injury -- Epidemiology of Severe Head Injury: Socio-economic Consequences of Avoidable Mortality and Morbidity -- Concussion Produces Dynamic Changes in Metabolism and Calcium Accumulation Resulting in Prolonged Neurological Deficits -- The Effect of Nimodipine Following Experimental Head Injury in Rats -- Spinal Cord Injury and the Possibilities of Treatment with Calcium Antagonists -- The Effect of Nimodipine on Outcome After Head Injury: A Prospective Randomized Controlled Trial

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