Title | Adjuvant Therapy of Primary Breast Cancer VI [electronic resource] / edited by Hans-Jรถrg Senn, Richard D. Gelber, Aron Goldhirsch, Beat Thรผrlimann |
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Imprint | Berlin, Heidelberg : Springer Berlin Heidelberg, 1998 |
Connect to | http://dx.doi.org/10.1007/978-3-642-45769-2 |
Descript | XVI, 506p. 73 illus. online resource |
I. Epidemiology and Its Lessons -- Diet and Mammary Gland Carcinogenesis -- Prevention of Breast Cancer: Focus on Chemoprevention -- Estrogen/Hormone Replacement Therapy and the Etiology of Breast Cancer -- II. Genetics of Breast Cancer -- Experimental Pathology and Breast Cancer Genetics: New Technologies -- Update on Breast Cancer Susceptibility Genes -- III. Biology of Breast Cancer: Diagnostic and Prognostic Implications -- IGF-I Physiology and Breast Cancer -- Determination of Clinical Utility of Tumor Markers: A Tumor Marker Utility Grading System -- How Can Prognostic and Predictive Factors in Breast Cancer Be Used in a Practical Way Today? -- Strategies for the Development of Vaccines to Treat Breast Cancer -- IV. In Situ Breast Cancer -- Hypothesis and Practice: Are There Several Types of Treatment for Ductal Carcinoma In Situ of the Breast? -- Ductal Carcinoma In Situ of the Breast: Histological Classification and Genetic Alterations -- Trials of Treatment for Non-invasive Breast Cancer -- Summary -- V. Controversies About the Axilla -- The Axilla: To Clear or Not to Clear? That Is the Question! -- Axillary Clearance in Operable Breast Cancer: Still a Necessity? -- Sentinel Lymphadenectomy: A Safe Answer to Less Axillary Surgery? -- Endoscopic Surgery to the Axilla: A Substitute for Conventional Axillary Clearance? -- VI. Integrated Therapy: Changing Surgical Procedures for Breast Cancer -- Surgical Considerations in Preoperative Chemotherapy of Breast Cancer -- Integration of Plastic Surgery in the Course of Breast-Conserving Surgery for Cancer to Improve Cosmetic Result and Radicality of Tumor Excision -- Summary -- VII. Integrated Therapy: Primary Adjuvant Systemic Therapy -- Is Primary Chemotherapy Useful for All Patients with Primary Invasive Breast Cancer? -- The Primary Use of Endocrine Therapies -- VIII. Integrated Therapy: Radiation Therapy/Endocrine Treatment -- Why and How to Combine Chemotherapy and Radiation Therapy in Breast Cancer Patients -- Novel Approaches Using Radiation Therapies -- Molecular Biology of the Estrogen Receptor Aids in the Understanding of Tamoxifen Resistance and Breast Cancer Prevention with Raloxifene -- Aromatase Inhibitors and Their Use in the Adjuvant Setting -- GnRH Analogues and Ovarian Ablation: Their Integration in the Adjuvant Strategy -- Summary -- IX. Adjuvant Systemic Treatments: Cytotoxic Strategies -- Putting the Taxanes to Work: Unanswered Questions -- Putting Taxanes to Work in Operable Breast Cancer: A Search for Selective Indications from Empirical Studies -- Continuous Infusional Chemotherapy for Early Breast Cancer: The Royal Marsden Hospital Experience -- Tailored Chemotherapy to Equal Toxicity: Is It Possible? -- Anti-angiogenesis Therapy and Strategies for Integrating It with Adjuvant Therapy -- X. Adjuvant Systemic Treatments: Cytotoxics and Their Dosage -- New Developments in High-Dose Chemotherapy for Breast Cancer -- Summary -- XI. Integrated Treatments: Quality of Life -- Quality of Life Assessment in the Adjuvant Setting: Is It Relevant? -- Quality of Life Assessment in the International Breast Cancer Study Group: Past, Present, and Future -- Impact of Different Adjuvant Therapy Strategies on Quality of Life in Breast Cancer Survivors -- Summary -- XII. Clinical Research Around the World: Review of Cooperative Group Trials -- North American Adjuvant Breast Cancer Trials -- International Breast Cancer Study Group Trials -- Nordic Trials of Adjuvant Therapy in Primary Breast Cancer -- The EORTC-Breast Cancer Cooperative Group Clinical Research Programme in Early Breast Cancer -- Italian Breast Cancer Adjuvant Chemo-hormone Therapy Cooperative Group Trials -- Current Trials of the German Adjuvant Breast Cancer Group (GABG) -- XIII. International Consensus Conference on Primary Treatment of the Breast: Update 1998 -- International Consensus Panel on the Treatment of Primary Breast Cancer V: Update 1998