Author | Schwartz, Laurent. author |
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Title | Cancer โ Between Glycolysis and Physical Constraint [electronic resource] / by Laurent Schwartz |
Imprint | Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2004 |
Connect to | http://dx.doi.org/10.1007/978-3-642-18543-4 |
Descript | XVIII, 150 p. 24 illus. online resource |
1 Introduction -- 2 Are Cancer Cells Malignant Per Se? -- 3 Cell Growth: A Balance Between Glycolysis and Physical Constraint -- 4 Extracellular Constraints Regulate Cell Differentiation -- 5 Extracellular Constraints Regulate Cell Differentiation -- 6 Hypoxia Is Responsible for Changes in Cellular Constraints During Inflammation -- 7 Fibrosis Perpetuates Hypoxia -- 8 Metastasis: The Hunt for Food -- 9 Carcinogens Target Cell Respiration and Induce Glycolysis -- 10 Epidemiology: Aging as the Main Cause of Cancer -- 11 Aging Causes Inflammation and Fibrosis Mimicking the Impact of Carcinogens -- 12 Inhibition of Metabolism Slows Aging and Decreases Cancer Incidence -- 13 A Complication of Hypoxia: The Loss of Cell Polarity Explains Cancer Cell Proliferation -- 14 The Loss of Cell Differentiation Is a Consequence of Glycolysis -- 15 Response to Treatment: A Balance Between Glycolysis and Physical Constraints -- 16 Targeting Glycolysis -- 17 Conclusion