Title | NMDA Antagonists as Potential Analgesic Drugs [electronic resource] / edited by Dalip J. S. Sirinathsinghji, Ray G. Hill |
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Imprint | Basel : Birkhรคuser Basel : Imprint: Birkhรคuser, 2002 |
Connect to | http://dx.doi.org/10.1007/978-3-0348-8139-5 |
Descript | VIII, 194 p. online resource |
Pharmacology and electrophysiology of excitatory amino acid receptors -- Distribution of NMDA receptors in brain and spinal cord -- Spinal nociceptive processing: NMDA receptors and modulation by neuropeptides -- The NMDA receptor, pain and central sensitization -- Some pharmacological aspects of NMDA-mediated nociceptive transmission in the rat spinal cord as revealed by c-fos immunocytochemistry -- Interaction of NMDA and other neurotransmitter receptor systems in modulation of nociception -- Behavioural studies on the potential of NMDA receptor antagonists as analgesics -- Clinically available glutamate receptor antagonists in neuropathic pain states -- Future prospects for improved analgesic therapy