Pharmacology and electrophysiology of excitatory amino acid receptors -- Distribution of NMDA receptors in brain and spinal cord -- Spinal nociceptive processing: NMDA receptors and modulation by neuropeptides -- The NMDA receptor, pain and central sensitization -- Some pharmacological aspects of NMDA-mediated nociceptive transmission in the rat spinal cord as revealed by c-fos immunocytochemistry -- Interaction of NMDA and other neurotransmitter receptor systems in modulation of nociception -- Behavioural studies on the potential of NMDA receptor antagonists as analgesics -- Clinically available glutamate receptor antagonists in neuropathic pain states -- Future prospects for improved analgesic therapy