Title | Mechanisms and Mediators of Neuropathic Pain [electronic resource] / edited by Annika B. Malmberg, Sandra R. Chaplan |
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Imprint | Basel : Birkhรคuser Basel : Imprint: Birkhรคuser, 2002 |
Connect to | http://dx.doi.org/10.1007/978-3-0348-8129-6 |
Descript | XII, 260 p. online resource |
Peripheral consequences of nerve injury -- Electrophysiological characteristics of injured peripheral nerves -- Sodium channels and the molecular basis for pain -- Changes in DRG neurons after injury: possible involvement in the development and maintenance of neuropathic pain -- Neuroinflammation, cytokines and neuropathic pain -- Spinal cord plasticity following peripheral nerve injury -- Pharmacological plasticity associated with neuropathic pain states -- Sprouting and reorganization in the spinal cord after nerve injury -- Neuropathic pain: preclinical and clinical paradigms -- Pre-clinical nerve ligation models: behavior and electrophysiology -- Animal models of toxic and metabolic sensory neuropathies -- Role of adrenergic transmitters and receptors in nerve and tissue injury related pain -- Evaluation of neuropathic pain -- New treatment strategies for neuropathic pain -- Glutamate receptor antagonists and neuropathic pain -- Antiepileptic drugs for treatment of neuropathic pain -- Calcium channel antagonists for the treatment of pain -- Cholinergic, adenosinergic and a2 adrenergic mechanisms in chronic neuropathic pain