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TitleInflammation and Cardiac Diseases [electronic resource] / edited by Giora Z. Feuerstein, Peter Libby, Douglas L. Mann
ImprintBasel : Birkhรคuser Basel : Imprint: Birkhรคuser, 2003
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Descript XV, 419 p. online resource


Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure


Inflammation โ{128}{147} a new frontier in cardiac disease and therapeutics -- Pathological aspects and inflammation biomarkers in cardiac diseases -- A biomarker of inflammation in cardiovascular diseases -- Inflammation and coronary artery disease -- Inflammatory cells and their metalloproteinases in cardiac diseases -- The role of matrix metalloproteinases in LV remodeling following myocardial infarction -- Matrix metalloproteinases in heart failure: evidence from experimental models -- Inflammatory cytokines in cardiac diseases -- The clinical experience with anti-cytokine therapy in heart failure -- The role of IL-6 and related cytokines in myocardial remodeling and inflammation โ{128}{147} implication for cardiac hypertrophy and heart failure -- Toll-like receptors and the cardiovascular system -- The role of IL-6 in experimental and clinical heart failure -- Oxygen and nitrogen reactive radicals in cardiac inflammation and disease -- Myocardial nitric oxide in cardiac remodeling -- Identification and role of inflammatory oxygen free radicals in cardiac ischemia and reperfusion injury -- The immune and complement system and cardiac diseases -- Immune-mediated myocarditis and interleukin-10 -- Immunomodulation in heart failure: experimental models -- The role of complement in myocardial inflammation and reperfusion injury -- Inflammatory signaling pathways in cardiac diseases -- The role of immune and inflammatory cytokines in ischemic preconditioning of the heart โ{128}{147} identification of novel cardiac cell survival signaling programs -- Stress-activated signals and their role in myocardial ischemia -- p38 MAPK in cardiac remodeling and failure: cytokine signaling and beyond -- Inflammation and myocarditis -- Inflammation and myocarditis -- The inflammatory process in experimental myocarditis -- Nuclear factors in cardiac disease -- Peroxisome proliferator activated receptors, inflammation, the vasculature and the heart -- Chemokines and cardiac diseases -- Role of chemokines in the pathogenesis of congestive heart failure -- Neurohormonal mediators and cardiac inflammation -- The role of endothelin-1 in myocardial inflammation and fibrosis -- Cyclooxygenases and cardiac diseases -- Cyclo-oxygenase-2 and myocardial ischemia -- Inflammation and arrhythmias -- Inflammation as a cause and consequence of atrial fibrillation -- Summary: Immune and inflammatory modulators as potential therapeutic targets for cardiac diseases

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