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TitleManagement of Prostate Cancer [electronic resource] / edited by Eric A. Klein
ImprintTotowa, NJ : Humana Press : Imprint: Humana Press, 2004
Edition Second Edition
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Descript XVII, 667 p. online resource


In this second edition of his popular and widely acclaimed book, Eric Klein, MD, and a panel of leading authorities have thoroughly updated and revised its contents to include all the latest observations and developments that will shape the direction of clinical practice and research over the next 5-10 years. Here, the reader will find in concise form accounts of the latest trends in diagnosis and mortality, new PSA isoforms for diagnosis, PSA screening, chemoprevention, biopsy techniques, sural nerve grafting, and hereditary prostate cancer. Additional chapters reflect progress in the management of locally advanced disease, the use of nomograms to predict outcomes, the medical management of erectile dysfunction, brachytherapy, and deciding between surgery and radiation. The chapters on open and laparoscopic techniques, the selection of candidates for observation, pathological analysis, quality of life, and the management of rising PSA after definitive therapy have been extensively updated. A compact disk accompanies the book for downloading an ebook to the reader's PC or PDA. Up-to-date and eminently practice-oriented, Management of Prostate Cancer, Second Edition, offers every physician-especially front-line urologists, radiation therapists, and medical oncologists-concise and authoritative guidance on today's best therapeutic regimens for the diagnosis and treatment of prostate cancer


I. Screening, Risk Factors, Diagnosis, and Prevention -- 1 Prostate Cancer Overdiagnosis and Overtreatment: Analysis of US Mortality and SEER Incidence Trends in the PSA and Pre-PSA Eras -- 2 Total, Complexed, and Free PSA Forms and Human Glandular Kallikrein 2: Clinical Application for Early Detection and Staging of Prostate Cancer -- 3 Defining an Optimum PSA-Based Screening Strategy for Young Men -- 4 Hereditary Prostate Cancer and Genetic Risk -- 5 Strategies for the Chemoprevention of Prostate Cancer -- 6 The Special Problems of Prostate Cancer Among African Americans: Clinical and Molecular Factors -- 7 Current Issues in Pathologic Evaluation -- 8 Current Trends in Biopsy Techniques -- II. Localized Disease: Treatment and Outcomes -- 9 Predicting Outcomes: Artificial Neural Networks and Nomograms -- 10 When Is Observation Appropriate? -- 11 Contemporary Technique of Radical Prostatectomy: Open Approach -- 12 Contemporary Technique of Radical Prostatectomy: Laparoscopic Approach -- 13 Contemporary Technique of Radical Prostatectomy: Perineal Approach -- 14 Anesthetic Considerations for Contemporary Radical Prostatectomy -- 15 Conformal External Beam Radiotherapy -- 16 Brachytherapy -- 17 Androgen Deprivation and Radiation Therapy for Localized Prostate Cancer -- 18 Prostate Brachytherapy: The Role of Supplemental External Beam Radiotherapy -- 19 Health-Related Quality of Life Issues -- 20 The Evaluation and Management of Postprostatectomy Urinary Incontinence -- 21 Sural Nerve Grafting During Radical Prostatectomy: Techniques and Results -- 22 Management of Erectile Dysfunction Following Radical Prostatectomy -- 23 Counseling Patients With Localized Prostate Cancer: Radiation or Surgery? -- 24 Counseling the Patient With Prostate Cancer: The Radiation Oncologistโ{128}{153}s Perspective -- 25 Counseling Patients on Choice of Therapy: The Medical Oncologistโ{128}{153}s Perspective -- 26 Emotional and Informational Support for the Patient Undergoing Radical Prostatectomy -- 27 Prostate Cancer: A Survivorโ{128}{153}s View -- 28 Prostate Cancer: A Spouseโ{128}{153}s View -- III. Advanced Disease -- 29 Management of PSA Recurrence After Definitive Therapy for Prostate Cancer -- 30 When to Refer a Patient With Prostate Cancer to a Medical Oncologist: The Earlier the Better -- 31 Management of Newly Diagnosed Metastatic Disease -- 32 Management of the Patient With Androgen-Independent Metastatic Prostate Cancer -- 33 Bone-Targeted Therapy for Prostate Cancer -- IV. Applied Molecular Biology -- 34 Biology of PSMA As a Diagnostic and Therapeutic Target -- 35 Opportunities for Targeted Molecular Therapy for Prostate Cancer

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