Title | Cancer Chemoprevention [electronic resource] : Promising Cancer Chemopreventive Agents / edited by Gary J. Kelloff, Ernest T. Hawk, Caroline C. Sigman |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2004 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-767-3 |
Descript | XVI, 697 p. 59 illus., 1 illus. in color. online resource |
I. Antimutagens -- 1 Inducers of Enzymes That Protect Against Carcinogens and Oxidants: Drug- and Food-Based Approaches with Dithiolethiones and Sulforaphane -- 2 Chemoprevention by Isothiocyanates -- 3 Antigenotoxic and Cancer Preventive Mechanisms of N-Acetyl-l-Cysteine -- 4 Modifiers of Cytochrome(s) P450 -- II. Antiinflammatories -- 5 Antiinflammatories and Chemoprevention: NSAIDs and Other Inhibitors of Arachidonic Acid Metabolism -- 6 Cyclooxygenase-2 Inhibitors and Colorectal Cancer Prevention -- 7 Lipoxygenases as Targets for Cancer Prevention -- 8 Inducible Nitric Oxide Synthase as a Target for Chemoprevention -- 9 Chemoprevention of Cancer of the Respiratory Tract by Agents Delivered by Aerosol: Applications to Glucocorticoids and 5-Fluorouracil -- 10 Chemoprevention of Cancer by Curcumin -- 11 Prostacyclin and Lung Cancer Chemoprevention -- III. Nuclear Receptor Superfamily -- 12 Nuclear Receptor Superfamily: Targets for Chemoprevention -- 13 Prostate Cancer Chemoprevention: S?-Reductase Inhibitors -- 14 Searching for SARA: The Role of Selective Androgen-Receptor Antagonists in Prostate Cancer -- 15 Aromatase Inhibitors as Chemopreventives of Breast Cancer -- 16 Breast Cancer Chemoprevention by Selective Estrogen Receptor Modulators -- 17 Chemopreventive Efficacy of Natural Vitamin D and Synthetic Analogs -- 18 The Retinoids and Cancer Chemoprevention -- 19 Biologic and Therapeutic Effects of Dehydroepiandrosterone and Structural Analogs -- IV. Signal Transduction Modulators -- 20 ras Oncogene Inhibitors -- 21 The Potential of EGFR-Targeted Agents in Cancer Prevention -- 22 Pharmacological Intervention with Multistep Oncogenesis: Potential Role for HSP90 Molecular Chaperone Inhibitors -- 23 Therapeutic Strategies Targeting Polyamines -- 24 The Role of Phytoestrogens as Cancer Prevention Agents -- 25 Cancer Chemopreventive Activity of Monoterpenes and Other Isoprenoids -- 26 Development of an Inhibitor of raf Kinase -- 27 Abnormalities in Cell Cycle Control in Human Cancer and Their Relevance to Chemoprevention -- 28 Select Cyclic Nucleotide Phosphodiesterase Inhibitors in Colon Tumor Chemoprevention and Chemotherapy -- V. Antioxidants, Vitamins, and Minerals -- 29 Chemoprevention by Fruit Phenolic Compounds -- 30 Tea Polyphenols as Cancer Chemopreventive Agents -- 31 Vitamin E as a Cancer Chemopreventive Agent -- 32 Vitamin C as a Cancer Chemopreventive Agent -- 33 Carotenoids -- 34 Lycopene, a Dietary Cancer Chemopreventive Agent -- 35 Not All Chemopreventive Selenium Compounds are Created Equal -- 36 Calcium -- 37 Folate and Cancer Chemoprevention -- 38 Conjugated Linoleic Acid as a Tumor Preventive Agent -- 39 Chemopreventive Effects of Omega-3 Fatty Acids -- VI. Agents Targeting Biological Processes Important in Cancer -- 40 Tumor Angiogenesis as a Target for Early Intervention and Cancer Prevention -- 41 Proteasome Inhibitors in Cancer Therapy -- 42 Modulation of DNA Methylation for the Treatment and Prevention of Cancer -- 43 Targeting Histone Deacetylase as a Strategy for Cancer Prevention