Title | Cancer Immunotherapy at the Crossroads [electronic resource] : How Tumors Evade Immunity and What Can Be Done / edited by James H. Finke, Ronald M. Bukowski |
---|---|
Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2004 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-743-7 |
Descript | XVII, 386 p. online resource |
I. Basic Mechanisms of Immune Evasion -- 1 HLA Class I Antigen-Processing Machinery and HLA Class I Antigen-Derived Peptide-Complex Defects in Tumor-Cell Escape -- 2 Immune Defects in T Cells From Cancer Patients: Parallels in Infectious Diseases -- 3 Malfunction of the Dendritic Cell System in Cancer -- 4 CD4+ T-Cell-Mediated Immunity to Cancer -- 5 Immunological Ignorance in Cancer -- 6 The Role of Receptor-Mediated Apoptosis in T-Cell Dysfunction -- 7 Alterations in T-Cell Signaling Pathways and Increased Sensitivity to Apoptosis -- 8 The Role of Tumor Gangliosides in the Immune Dysfunction of Cancer -- 9 Interleukin-l0-Induced Immune Suppression in Cancer -- 10 Accentuating Tumor Immunity Through Costimulation: A Detailed Analysis of OX40 Engagement and CTLA-4 Blockade -- 11 Optimizing T-Cell Adoptive Immunotherapy to Overcome Tumor Evasion -- 12 Tumor Resistance to Apoptosis: Mechanisms of Evasion and Implications for Radiation and Chemotherapeutic Strategies -- II. Clinical Relevance of Immune Evasion -- 13 The Development and Reversal of T-Cell Tolerance in Cancer Patients Receiving Peptide-Based Vaccines -- 14 Altered Signaling in T Lymphocytes of Patients With Cancer: A Biomarker of Prognosis? -- 15 Allogeneic Hematopoietic Blood-Cell Transplantation as Immunotherapy for Metastatic Renal Cell Carcinoma -- 16 Immune Defects in Patients Suffering From Non-Hodgkinโs Lymphoma -- 17 Immune Dysfunction in Classical Hodgkinโs Lymphoma -- 18 Lung Cancer and Immune Dysfunction -- 19 Primary Malignant Brain Tumors: Immune Defects and Immune Evasion