Title | Apoptosis and Cancer Chemotherapy [electronic resource] / edited by John A. Hickman, Caroline Dive |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 1999 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-720-8 |
Descript | XV, 342 p. online resource |
1 Does Apoptosis Contribute to Tumor Cell Sensitivity to Anticancer Agents? -- 2 p53, Apoptosis, and Chemotherapy -- 3 The Role of p53 in Chemosensitivity -- 4 Function of the p53 Gene Family: A Holistic Perspective -- 5 Mismatch Repair Deficiency, Apoptosis, and Drug Resistance -- 6 Involvement of c-Abl Tyrosine Kinase in Apoptotic Response to Anticancer Agents -- 7 Bcl-2 Family Proteins: Relative Importance as Determinants of Chemoresistance in Cancer -- 8 Bax, a Death Effector Molecule: Its Role in Development and Oncogenesis -- 9 Bax, a Proapoptotic Protein Forming Channels in Mitochondria -- 10 Mechanism of Action of the Proapoptotic Gene Bak -- 11 Killers or Clean-Up Crew: How Central Are the Central Mechanisms of Apoptosis? -- 12 Role of CD95 (APO-1/Fas) System in Chemotherapy -- 13 Insulin-Like Growth Factor-1 Receptor as a Target for Anticancer Therapy -- 14 Drug Resistance and the Survival Niche: Survival Signals Combine to Suppress Drug-Induced Apoptosis in B-Lymphoma Cells -- 15 Chemotherapy, Tumor Microenvironment, and Apoptosis -- 16 Molecular Regulation and Therapeutic Implications of Cell Death in Prostate Cancer -- 17 Chemotherapy and Apoptosis in the Ovary: Cancer Treatment Comes with a Price -- 18 Role of Bcl-2 Family Members in Homeostasis, in Toxicology in Normal Intestine, and for Prognosis of Colonic Carcinomas -- 19 Apoptosis and Breast Cancer -- 20 Role of Apoptosis in Human Neuroblastomas -- 21 Response of Testicular Tumors to Chemotherapy: Relative Role of DrugโDNA Interactions and Apoptosis -- Concluding Remarks: Has the Information Explosion on Apoptosis Affected Clinical Practice?