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TitleHormone Resistance Syndromes [electronic resource] / edited by J. Larry Jameson
ImprintTotowa, NJ : Humana Press : Imprint: Humana Press, 1999
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Descript X, 282 p. online resource


In Hormone Resistance Syndromes, leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. In addition to helping discover additional resistance syndromes, readers are afforded a unique opportunity to understand hormone action in normal physiology. Timely and authoritative, Hormone Resistance Syndromes provides an insightful survey of this critical area, one that will serve as a gold-standard reference for all those clinicians and researchers actively studying these mutations today


1 Dwarfism: GHRH Resistance -- 2 Laron Syndrome: Primary Growth Hormone Resistance -- 3 Pseudohypoparathyroidism -- 4 Hereditary Resistance to Vitamin D -- 5 Decreased Responsiveness to Extracellular Ca2+ Owing to Abnormalities in the Cao2+-Sensing Receptor -- 6 Resistance to TSH -- 7 Thyroid Hormone Resistance -- 8 Diabetes Mellitus: Insulin Resistance -- 9 LH Insensitivity Syndrome -- 10 FSH Resistance -- 11 Genetic Alterations of Androgen Receptor Function -- 12 Retained Mรผllerian Ducts: AMH Resistance Syndrome -- 13 Adrenal Insufficiency: ACTH Resistance -- 14 Glucocorticoid Resistance and Hypersensitivity

Medicine Endocrinology Medicine & Public Health Endocrinology


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