Title | Antiangiogenic Agents in Cancer Therapy [electronic resource] / edited by Beverly A. Teicher |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 1999 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-453-5 |
Descript | XI, 450 p. 37 illus., 1 illus. in color. online resource |
I. Antiangiogenic Factors and Tumor Vasculature -- 1 Angiogenesis and Blood Flow in the Solid Tumors -- 2 Oxygenation of Solid Tumors in Animals and Patients -- 3 Role of Inflammatory Mediators in Angiogenesis -- 4 Intra- and Extracellular pH in Solid Tumors -- 5 Contribution of the Extracellular Matrix and Macrophages in Angiogenesis -- 6 Regulation of Angiogenesis by the Organ Microenvironment -- 7 Fibroblast Growth Factors in Tumor Progression and Angiogenesis -- 8 Role of Vascular Endothelial Growth Factor in Regulation of Angiogenesis -- 9 Regulatory Aspects of Neovascularization: Regulation of Wound Angiogenesis by Metabolic Alterations -- II. Antiangiogenic Agents -- 10 Squalamine: A New Angiostatic Steroid -- 11 Cartilage as a Source of Natural Inhibitors of Angiogenesis -- 12 Thrombospondin as an Inhibitor of Angiogenesis -- 13 Matrix Metalloproteinase Inhibitors -- 14 Angiostatin and Other Plasminogen Fragments -- 15 Dietary and Nutritional Modulation of Tumor Angiogenesis -- 16 Thalidomide and Analogs -- III. In Vivo Studies and Clinical Trials -- 17 Potentiation of Cytotoxic Cancer Therapies by Antiangiogenic Agents -- 18 Prognostic Significance of Tumor Vascularity -- 19 Endpoints for Determination of Efficacy of Antiangiogenic Agents in Clinical Trials -- 20 Retinoids and Interferons as Antiangiogenic Cancer Drugs -- 21 Pentosan Polysulfate: A Polysaccharide That Inhibits Angiogenesis by Binding Growth Factors -- 22 TNP-470 -- 23 Batmastat and Marmastat in Cancer: Summary of Early Clinical Data -- 24 Thalidomide: A Prodrug That Inhibits Angiogenesis -- 25 Ribozyme Targeting of Angiogenic Molecules