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TitleMolecular and Cellular Basis of Inflammation [electronic resource] / edited by Charles N. Serhan, Peter A. Ward
ImprintTotowa, NJ : Humana Press : Imprint: Humana Press, 1999
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Descript XII, 338 p. online resource


In Molecular and Cellular Basis of Inflammation, Charles N. Serhan and Peter A. Ward bring together a collection of cutting-edge reviews of the molecular and cellular bases of inflammatory processes. Their authoritative new book reviews the role of protein and lipid mediators in inflammation, cellular processes of importance in the initiation and determination of inflammation, signal transduction events of interest in the development of potential new therapeutic targets, and drug design issues in inflammation therapeutics. In addition, several chapters summarize state-of-the-art findings in disease processes where inflammation plays a critical role. Reflecting the work of leading researchers in molecular biology, biochemistry, pharmacology, immunology, and pathobiology, Molecular and Cellular Basis of Inflammation offers a powerful new synthesis of our understanding of inflammatory processes and diseases today, as well as an insightful contribution to the search for new antiinflammatory agents


Ch. 1. Role of Complement in Endothelial Cell Activation -- Ch. 2. Angiogenesis -- Ch. 3. Update on Arachidonic Acid Cascade: Leukotrienes and Lipoxins in Disease Models -- Ch. 4. Mutagenesis Studies of Mammalian Lipoxygenases -- Ch. 5. Lipid-Mediator-Deficient Mice in Models of Inflammation -- Ch. 6. Isoprostanes in the Assessment of Oxidant Stress In Vivo -- Ch. 7. Isoprostanes as Markers of Lipid Peroxidation in Atherosclerosis -- Ch. 8. Structure and Regulation of NADPH Oxidase of Phagocytic Leukocytes: Insights from Chronic Granulomatous Disease -- Ch. 9. Recruitment of ?/? T-Cells and Other T-Cell Subsets to Sites of Inflammation -- Ch. 10. The N-Formyl Peptide Receptor: Structure, Signaling, and Disease -- Ch. 11. Pathobiology of Neutrophil Interactions with Polarized Columnar Epithelia -- Ch. 12. Adenosine and Its Receptors During Inflammation -- Ch. 13. Quantitative Studies of the Lipid Mediators of Inflammation Using Liquid Chromatography-Electrospray Mass Spectrometry -- Ch. 14. Molecular Biology of Autoimmune Arthritis -- Ch. 15. Lupus Erythematosus: The Role of Adhesion Molecules and Local Mediators

Medicine Immunology Biomedicine Immunology


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