Title | Gene Engineering in Endocrinology [electronic resource] / edited by Margaret A. Shupnik |
---|---|
Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2000 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-221-0 |
Descript | XII, 428 p. online resource |
I Growth, Development, and Metabolism -- 1 Differential Cell Signaling and Gene Activation by the Human Growth Hormone Receptor: From Cell Surface to Cell Nucleus -- 2 Insulin Action: Molecular Mechanisms and Determinants of Specificity -- 3 Ets Transcription Factors: Nuclear Integrators of Signaling Pathways Regulating Endocrine Gene Expression and Carcinogenesis -- 4 Pit-1 Expression, Regulation, and Modulation of Multiple Pituitary Genes -- 5 Subnuclear Trafficking of Glucocorticoid Receptors: General Mechanisms and Specific Recruitment to a Unique Target Site by Tethering to a DNA-Bound POU Domain Protein -- 6 Thyroid Hormone Receptors and Their Multiple Transcriptional Roles -- 7 Models of Resistance to Thyroid Hormone -- 8 Thyroid Hormone Receptor Family Members: Homodimers, Heterodimers, and Mechanisms of Transcriptional Repression -- 9 SF-1 and DAX-1: A Dynamic Duo in Endocrine Development -- II Reproductive System -- 10 Gene Knockout Models to Study the Hypothalamus-Pituitary-Gonadal Axis -- 11 Transgenic Approaches to Study Developmental Expression and Regulation of the Gonadotropin Genes -- 12 Molecular Events Defining Follicular Developments and Steroidogenesis in the Ovary -- 13 Regulation of Inhibin Subunit Gene Expression by Gonadotropins and cAMP in Ovarian Granulosa Cells -- 14 Placental Trophoblast Cells: Transcriptional Regulation and Differentiation -- 15 Alternative Splicing of mRNAs for cAMP-Responsive Transcriptional Factors and Modulation of Gene Transcription in the Testis -- 16 The Androgen Receptor, Androgen Insensitivity, and Prostate Cancer -- 17 Genetic Determination of Androgen Responsiveness -- 18 Steroid Receptor Regulation by Phosphorylation and Cell Signaling Pathways -- 19 Steroid Receptor Actions: Agonists and Antagonists and the Role of Coactivators and Corepressors