Title | The Molecular Basis of Human Cancer [electronic resource] / edited by William B. Coleman, Gregory J. Tsongalis |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 2002 |
Connect to | http://dx.doi.org/10.1007/978-1-59259-125-1 |
Descript | XII, 588 p. online resource |
I. Introduction -- 1 Cancer Epidemiology: Incidence and Etiology of Human Neoplasms -- II. Essential Concepts in Molecular Biology -- 2 Essential Concepts and Techniques in Molecular Biology -- III. Molecular Themes in Oncogenesis -- 3 Cancer Genes -- 4 Positive Mediators of Cell Proliferation in Neoplastic Transformation -- 5 Inactivation of Negative Growth Regulators During Neoplastic Transformation -- IV. Mechanisms of Mutation -- 6 The Role of Genomic Instability in the Development of Human Cancer -- 7 Chromosomes and Chromosomal Instability in Human Cancer -- 8 Hereditary Cancer -- V. Etiology of Human Cancers -- 9 Evolution of Research in Cancer Etiology -- 10 Cellular Responses to Chemical Carcinogens -- 11 Physical Agents in Human Carcinogenesis -- 12 Viral Mechanisms of Human Carcinogenesis -- VI. Human Tumor Systems -- 13 The Molecular Biology of Colorectal Carcinoma: Importance of the Wg/Wnt Signal Transduction Pathway -- 14 Molecular Genetic Alterations in Primary Hepatocellular Neoplasms: Hepatocellular Adenoma, Hepatocellular Carcinoma, and Hepatoblastoma -- 15 The Molecular Basis of Breast Carcinogenesis -- 16 The Molecular Basis of Prostate Carcinogenesis -- 17 The Molecular Basis of Lung Carcinogenesis -- 18 The Molecular Basis of Skin Carcinogenesis -- 19 The Molecular Biology of Leukemias -- 20 Molecular Genetic Applications to the Diagnosis of Non-Hodgkinโs Lymphoma -- VII. Future Directions -- 21 Cancer Genetic Counseling -- 22 Molecular Genetic Diagnosis of Inherited Cancer Predisposition -- 23 Novel Molecular Targets for Cancer Drug Discovery -- 24 Gene Therapy in the Treatment of Human Cancer