Title | The New Dimensions of Warfarin Prophylaxis [electronic resource] / edited by Stanford Wessler, Carl G. Becker, Yale Nemerson |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1987 |
Connect to | http://dx.doi.org/10.1007/978-1-4757-5985-3 |
Descript | IX, 329 p. online resource |
The Scope of Thromboembolism -- Vitamin K-Dependent Proteins -- The Biochemical Basis of Warfarin Therapy -- Warfarin and the Biochemistry of the Vitamin K Dependent Proteins -- Anticoagulation Proteins C and S -- Warfarin and Bone: Implications for Rational Strategies to Selectively Antagonize the Action of Vitamin K in Target Tissues -- Human Genes for Factor IX and Other Vitamin K Dependent Blood Proteins -- The Prothrombin Time -- Tissue Factor -- INR โ Calibration of the Therapeutic Range -- Cold-Promoted Activation of Factor VII and Shortening of the Prothrombin Time -- Immunologic Aspects of Vessel Injury and Thrombosis -- Whatโs The Dose? -- Venous Thromboembolism โ Primary Prophylaxis -- Venous Thromboembolism in Moderate Risk Patients -- Two-Step Warfarin Therapy for the Prophylaxis of Venous Thrombosis after Elective Surgery -- Prevention of Venous Thromboembolism in High-Risk Patients by Prophylactic Administration of Oral Anticoagulants -- Genetic Coagulation Defects -- Venous Thromboembolism โ Secondary Prophylaxis -- Treatment of First Episode of Venous Thrombosis -- Management of Recurrent Venous Thromboembolism -- Special Issues -- Warfarin Metabolism and Drug-Drug Interactions -- Improving the Benefit/Risk Ratio -- Oral Anticoagulant Therapy and Skin Necrosis: Speculations on Pathogenesis -- Cardiovascular โ Arterial Thromboembolism -- Clinical Trials in Myocardial Infarction and Coronary Heart Disease -- Anticoagulants in Acute Myocardial Infarction -- Long-Term Anticoagulant Treatment after Acute Myocardial Infarction -- Following Coronary Thrombolysis -- Arterial Thromboembolism: Valvular Heart Disease and Prosthetic Heart Valves -- Neurovascular โ Arterial Thromboembolism -- Clinical Trial Dilemmas and Cerebrovascular Disease -- Atrial Fibrillation and Stroke: The View from Cardiology -- Atrial Fibrillation and Stroke: The View from Neurology -- Cardiac Embolic Stroke: Anticoagulating the Elderly -- Anticoagulants for the Treatment of Transient Ischemic Attacks -- Epilogue -- Contributors