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TitleVitamin D [electronic resource] : Molecular Biology, Physiology, and Clinical Applications / edited by Michael F. Holick
ImprintTotowa, NJ : Humana Press : Imprint: Humana Press, 1999
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Descript XII, 458 p. online resource


The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter referยญ virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authoriยญ ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences


1 Evolution, Biologic Functions, and Recommended Dietary Allowances for Vitamin D -- 2 Photobiology of Vitamin D -- 3 Functional Metabolism and Molecular Biology of Vitamin D Action -- 4 Metabolism and Catabolism of Vitamin D, Its Metabolites, and Clinically Relevant Analogs -- 5 The Enzymes Responsible for Metabolizing Vitamin D -- 6 The Vitamin D Binding Protein and Its Clinical Significance -- 7 Molecular Biology of the Vitamin D Receptor -- 8 Vitamin D Receptor Translocation -- 9 Molecular Recognition and Structureโ{128}{148}Activity Relations in Vitamin D-Binding Protein and Vitamin D Receptor -- 10 Mechanism of Action of 1,25-Dihydroxyvitamin D3 on Intestinal Calcium Absorption and Renal Calcium Transport -- 11 Biologic and Molecular Effects of Vitamin D on Bone -- 12 Nongenomic Rapid Effects of Vitamin D -- 13 Noncalcemic Actions of 1,25-Dihydroxyvitamin D3 and Clinical Implications -- 14 Regulation of Parathyroid Hormone Gene Expression and Secretion by Vitamin D -- 15 Vitamin D Assays and Their Clinical Utility -- 16 Rickets and Vitamin D Deficiency -- 17 Vitamin D and Bone Health in Adults and the Elderly -- 18 Inherited Defects of Vitamin D Metabolism -- 19 Molecular Defects in the Vitamin D Receptor Associated with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets -- 20 Extrarenal Production of 1,25-Dihydroxyvitamin D and Clinical Implications -- 21 Clinical Utility of 1,25-Dihydroxyvitamin D3 and Its Analogs for the Treatment of Psoriasis and Other Skin Diseases -- 22 Epidemiology of Cancer Risk and Vitamin D -- 23 Chemotherapeutic and Chemopreventive Actions of Vitamin D3 and Analogs -- 24 Vitamin D and Breast Cancer -- 25 Anticancer Activity of Vitamin D Analogs

Medicine Clinical nutrition Biochemistry Medicine & Public Health Clinical Nutrition Biochemistry general


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