Title | Cytokine Knockouts [electronic resource] / edited by Scott K. Durum, Kathrin Muegge |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 1998 |
Connect to | http://dx.doi.org/10.1007/978-1-4757-2753-1 |
Descript | XXV, 482 p. online resource |
Ch. 1. The IL-2 Deficiency Syndrome: A Lethal Disease Caused by Abnormal Lymphocyte Survival -- Ch. 2. IL-7 Knockout Mice and the Generation of Lymphocytes -- Ch. 3. Lymphoid Development and Function in IL-7R-Deficient Mice -- Ch. 4. CD40 Ligand Knockout Mice -- Ch. 5. Physiological, Immunological, and Pathological Functions of Tumor Necrosis Factor (TNF) Revealed by TNF Receptor-Deficient Mice -- Ch. 6. Cooperation Between the TNF Receptors Demonstrated by TNF Receptor Knockout Mice -- Ch. 7. Immunodeficiency of Tumor Necrosis Factor and Lymphotoxin-? Double-Deficient Mice -- Ch. 8. Characterization of Lymphotoxin-?-Deficient Mice -- Ch. 9. Interleukin-1?-Deficient Mice -- Ch. 10. Functional Phenotype of Mice Deficient in the IL-1R Type 1 Gene: A Comparison with Other Genetically Modified Mice -- Ch. 11. Mice Deficient in Interleukin-1? Converting Enzyme -- Ch. 12. Neutrophilia and B-Cell Plasmacytosis in Mice Lacking the Murine IL-8 Receptor Homolog -- Ch. 13. Knockouts of Interferons, Interferon Receptors and Interferon Signaling Components -- Ch. 14. IL-6 Gene Knockout Mice -- Ch. 15. IL-6 Unique Functions in Inflammation, Bone Metabolism, and B-Cell Neoplasias Revealed by Studies on IL-6 Deficient Mice -- Ch. 16. Myocardial, Hematological, and Placental Disorders Caused by Targeted Disruption of gp130, A Common Signal Transducer for IL-6 Family of Cytokines -- Ch. 17. NF-IL6 Knockout Mice -- Ch. 18. Disruption of the LIF Receptor -- Ch. 19. Phenotypes of TGF? Knockout Mice -- Ch. 20. The Transforming Growth Factor-?1 Knockout Mouse: The Phenotype and Its Implications for TGF?1 Function -- Ch. 21. Granulocyte-Macrophage Colony-Stimulation Factor (GM-CSF)-Deficient Mice -- Ch. 22. The In Vivo Role of the Receptors for IL-3, GM-CSF, and IL-5 (?c and ?IL3) -- Ch. 23. Granulocyte Colony-Stimulating Factor (G-CSF)-Deficient Mice -- Ch. 24. Reduction of Platelets and Megakaryocytes in c-mpl-Deficient Mice