Title | Etiopathogenesis [electronic resource] / edited by Yoshikuni Mizuno, Donald B. Calne, R. Horowski |
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Imprint | Boston, MA : Birkhรคuser Boston : Imprint: Birkhรคuser, 1994 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-9203-3 |
Descript | XIII, 223 p. 13 illus. online resource |
I: Genetic, Growth, and Environmental Factors -- 1 Genetic Evidence for a Novel Familial Alzheimerโs Disease Locus on Chromosome 14: Analysis of Candidate Genes -- 2 Growth factors in Parkinsonโs Disease -- 3 Contribution of Cell Culture to Understanding Neuronal Aging and Degradation -- 4 Neuroepidemiology of Parkinsonโs Disease: Environmental Influences -- 5 Discussion -- II: Metals and Free Radicals -- 6 Manganese-Induced Neurotoxicity -- 7 Iron and Parkinsonโs Disease -- 8 Biological Synthesis of Nitric Oxide from L-Arginine -- 9 Multiple Roles of the Calcium Ion in Cell Killing -- 10 Discussion -- III: Energy Metabolism and Neurotoxins -- 11 Mitochondrial Dysfunction, Aging, and Huntingtonโs Disease -- 12 Energy Failure, Glutamate, and Neuropathology: Relevance to Neurodegenerative Disorders -- 13 Proteases and Pathological Neurodegeneration -- 14 Endogenous MPTP-Like Amines in the Brain: Isoquinolines -- 15 Discussion -- IV: Special Topics in Neurodegeneration -- 16 Mitochondrial Disturbances in Parkinsonโs Disease -- 17 Trophic Factors and Parkinsonโs Disease -- 18 Spontaneous Generation of Infectious Amyloid Nucleants in the Transmissible and Nontransmissible Brain Amyloidoses -- 19 Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex of Guam: Two Distinct Clinical Entities or a Single Disease Process with a Spectrum of Neuropathological and Clinical Expression? -- 20 Discussion -- Erratum, Volume I, Page 69