Title | The Renal Papilla and Hypertension [electronic resource] / edited by Anil K. Mandal, Sven-Olof Bohman |
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Imprint | Boston, MA : Springer US, 1980 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-8115-0 |
Descript | XXIV, 238 p. online resource |
1 The Ultrastructure of the Renal Medulla and the Interstitial Cells -- 1. Introduction -- 2. The Renal Medulla -- 3. The Interstitial Cells -- References -- 2 Evidence for an Involvement of the Renal Papilla in Hypertension -- 1. Introduction -- 2. Antihypertensive Action of Transplants of Fragmented Renal Papilla -- 3. Monolayer Tissue Culture of RIC -- 4. Antihypertensive Action of Cultured RIC -- 5. Morphology of Transplants of Cultured RIC -- 6. The Lipid GranuleโCisternal Organelle Relationship of RIC -- 7. Renomedullary (RIC) Deficiency in Hypertension -- 8. Renomedullary Interstitial Cell Tumor -- 9. Inhibition of the Converting Enzyme (Kininase II) and the Action of RIC -- 10. Antihypertensive Lipids Derivable from Fresh Renal Medulla -- 11. Antihypertensive Action of Cultured RIC and of Lipids Derived from the Same Tissue Culture -- 12. Three Additional Special Features of RIC -- 13. Discussion -- References -- 3 Studies on the Mechanism of the Renomedullary Hypertensive Action -- 1. Introduction -- 2. Endocrine-Type Antihypertensive Activity of the Renal Medulla -- 3. The Mediator of Renomedullary Antihypertensive Function -- 4. What Signals the Medulla to Release Antihypertensive Renomedullary Substance? -- 5. The Mechanism of Renomedullary Antihypertensive Action -- 6. Concluding Remarks -- References -- 4 Vasodepressor Substances Extractable from Kidney Tissue -- 1. Introduction -- 2. Earlier Work on Antihypertensive Effects of Extracts of Whole Kidney Tissue -- 3. Renomedullary Antihypertensive Lipids -- 4. Renin Inhibitors and Phospholipases -- 5. Renal Kinins -- 6. Concluding Remarks -- References -- 5 Renal Prostaglandin Synthesis and Metabolism in Normal and Hypertensive States -- 1. Introduction -- 2. Renal Effects of Prostaglandins -- 3. Regulation of Prostaglandin Metabolism in the Kidney -- 4. Prostaglandins in Hypertension -- 5. Renomedullary Interstitital Cells and Prostaglandins -- 6. Renal Prostaglandin Metabolism in the Spontaneously Hypertensive Rat -- 7. Conclusions and Future Directions -- References -- 6 Fatty Acid Composition and Depot Function of Lipid Droplet Triacylglycerols in Renomedullary Interstitial Cells -- 1. Introduction -- 2. Isolation and Characterization of Papillary Lipid Droplets -- 3. Biochemical Investigations of the Renal Papilla -- 4. Comparison between in Vitro and in Vivo Data -- 5. Conclusion: The Physiological Role of the Lipid Droplets of Renomedullary Interstitial Cells -- References -- 7 Alterations in the Renal Medullary and Papillary Interstitial Cells in Experimental and Spontaneous (Essential) Hypertension -- 1. Introduction -- 2. Experimental Hypertensions -- 3. Value of Electron Microscopy in Defining the Chemical Nature of Papillary Interstitial Granules -- 4. Relationship of Renal Papillary Interstitial Granules to Essential (Spontaneous) Hypertension -- 5. Relationship of Interstitial Cellular Granules to Renomedullary Vasodepressor Substances -- 6. Significance of the Studies of the Renal Papillary Interstitial Cells in Rat -- 7. Obstacles to Human Study -- References -- 8 Regulation of Plasma Flow and Other Functions of the Renal Papilla in Hypertension -- 1. Studies of Plasma Flow to the Renal Papilla in Experimental and Spontaneous Hypertension -- 2. Relationship between Renomedullary Interstitial Cell Granules, Sodium, and Prostaglandins in Normotensive and Hypertensive Rats -- References -- 9 Prostaglandin E2 Biosynthesis by Renomedullary Interstitial Cells: In Vitro Studies and Patholphysiological Correlations -- 1 Introduction -- 2. Regulation of Arachidonic Acid Metabolism by Rabbit Renomedullary Interstitial Cells in Tissue Culture -- 3. Pathophysiological Correlations -- 4. Conclusions -- References -- 10 Influence of Renal Prostaglandins on Renin Release -- 1. Introduction -- 2. The Renin-Angiotensin System -- 3. The Renal Prostaglandins -- 4. Influence of Renal Prostaglandins on Renin Release -- 5. Prostaglandins and the Different Receptors for Renin Release -- 6. Impaired Prostaglandin Production and Unresponsiveness of Renin Secretion in Essential Hypertension -- 7. Conclusion -- References