Title | Mechanisms of Cerebral Hypoxia and Stroke [electronic resource] / edited by George Somjen |
---|---|
Imprint | Boston, MA : Springer US, 1988 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-5562-5 |
Descript | XII, 474 p. online resource |
Adaptation in Diving Vertebrates -- Inborn resistance to hypoxia and the O2-dependence of metabolism -- Brain vulnerability and survival during anoxia: protective strategies of hypoxia-resistant vertebrates -- General Pathology -- Early and late neuronal damage following cerebral ischemia -- Selective neuronal cell death after transient forebrain ischemia in the mongolian gerbil -- Possible implications of ischemic damage to dentate hilar somatostatin neurons in the rat -- Regulation of glutamate receptors in hippocampus after cerebral ischemia -- Role of edema in the pathophysiology of ischemic injury -- Acidosis-related brain damage immediate and delayed events -- Pathology of ischaemic brain damage: implications for therapy -- Ischemic damage of rat hippocampus and basal ganglia: light microscopical and biochemical changes -- Pathophysiology -- Physiological aspects of brain ischaemia in the experimental primate and man -- The dependency of cerebral ischemic damage on duration and severity of ischemia: studies of single cell activity and multimodality evoked responses -- Microcirculation and metabolism in reversible and irreversible cerebral ischemia -- Cerebral blood flow and its responsiveness to CO2 after traumatic and ischemic brain injuries -- The correlation between electrophysiological parameters (EEG, DC potential and tissue available O2) and regional metabolites (pH, ATP, glucose, NADH, K) after 45 min middle cerebral artery occlusion and 3 hours recirculation in cats -- Cerebral hypoxia during repetitive seizures -- Microcirculation, NAD/NADH fluorescence, extracellular potassium and glucose metabolism changes in focal cerebral ischemia -- Neurons, glia and ions in hypoxia, hypercapnia and acidosis -- Effects of anoxia on nerve cell function -- Reversible synaptic blockade caused by hypoxia of moderate degree in hippocampal tissue slices -- Anoxia reversibly inactivates hippocampal calcium currents -- Reversibility of neuronal function of hippocampal slice during deprivation of oxygen and/or glucose -- The effect of hypoxia on hippocampal neurones and its prevention by Ca2+-antagonists -- Anoxia in CA1 pyramidal cells: ionic and metabolic factors contributing to recovery of ion transport and synaptic transmission -- Long-term inhibition of synaptic transmission and macromolecular synthesis following anoxia in the rat hippocampal slice: interaction between Ca2+ and NMDA receptors -- Early alterations in striatal and hippocampal impedance and extracellular amino acids by cardiac arrest in freely moving rats -- Susceptibility to spreading depression and anoxia: regional differences and drug control -- Blood flow and metabolism in cortical spreading depression -- Dynamics of volatile buffers in brain cells during spreading depression -- The role of spreading depression-like hypoxic depolarization in irreversible neuron damage, and its prevention -- NMDA antagonists inhibit cortical spreading depression, but accelerate the onset of neuronal depolarization induced by asphyxia -- Does Leaoโs spreading depression cause irreversible brain damage? -- Electrophysiological and biochemical events in the isolated perfused rat brain under ischemia and reperfusion -- Neurotransmitter modulation of neuronal damage following cerebral ischemia: Effects on protein ubiquitination -- Detection of free radicals in cerebral tissue and their relation to cerebral hypoxia/ischemia -- Pharmacology -- The limits of reversibility from ischemic cerebral insult and our method of prolonging cerebral survival -- Excitatory amino acid neurotransmission and protection against ischaemic brain damage -- Excitatory amino acid and purinergic transmitter involvement in ischemia-induced selective neuronal death -- Protection of hippocampal neurons from โischemicโ insult in vitro by acidic amino acid antagonists -- Magnesium inhibits ischemia-induced calcium accumulation in hilar neurones: possible effect of NMDA-receptor -- Dopamine and the susceptibility of striatal neurons to ischemia -- Effects of flunarizine on normal and injured rat cerebral cortex -- Improvement of postischemic cell damage and energy metabolism in the rat by flunarizine and emopamil -- Discrimination between vascular and direct effects on cerebral parenchyma of emopamil -- Prophylaxis and therapy of hypoxic and ischemic brain: effects of monosialoganglioside GM1 -- Adenosine neuromodulation of selectively vulnerable CA1 neurons -- The nucleoside-transport inhibitor, mioflazine, increases recovery of hippocampal synaptic transmission and energy-rich metabolites after normothermic global ischemia -- Glutamine protects neuronal function against hypoxia in vitro -- Cerebroprotective effect of histamine receptor blockers in hypoxia-induced experimental brain edema -- Drug effects on cerebral extracellular ionic derangement during ischemic hypoxia -- Discussion and Conclusions -- General discussion: a synopsis -- Basic mechanisms in cerebral hypoxia and stroke: background, review and conclusions -- Author index