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AuthorKilbourne, Edwin D. author
TitleInfluenza [electronic resource] / by Edwin D. Kilbourne
ImprintBoston, MA : Springer US, 1987
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Descript 382 p. 56 illus. online resource


My lifetime encompasses the postwar subsidence in the early 1920s of the greatest influenza pandemic in history, direct encounters with FM1 virus at Fort Monยญ mouth in 1947, the care of influenza patients in the 1950s, the pursuit of the inยญ fluenza virus through the modern pandemics of 1957 and 1968, and a present in which the genes of the virus have dissembled in the DNA of vaccinia virus and Escherichia coli through the wand of "high tech. " If my corpus could be fossilized for archival and archaeological purposes, it would be found to contain immune cells branded with the imprint of the "swine" influenza virus of post-1918 and brain cells no less imprinted with memories of the abortive return of its descendant during America's bicentennial. But before that unlikely event, I wanted to try to make some sense out of this baffling disยญ ease and its viruses-expecting no definitive revelations but hoping for a sharper definition of problems. Hence this book. It is an audacious act in these days of specialization to essay a book such as this singlehandedly, but I have done so for selfish reasons. I wanted to reexamยญ ine old questions about the nature of influenza and its epidemics in the light of the dazzling advances in molecular biology of the past few years. No virus has been better studied, but few diseases are less well understood


I. Introduction -- 1. History of Influenza -- II. The Influenza Viruses -- 2. Taxonomy and Comparative Virology of the Influenza Viruses -- 3. Viral Structure and Composition -- 4. Replication of Influenza Viruses -- 5. Cytopathogenesis and Cytopathology of Influenza Virus Infection of Cells in Culture -- 6. Influenza Virus Genetics, Viral Adaptation, and Evolution -- III. Influenza: Infection And Disease -- 7. Influenza in Man -- 8. The Laboratory Diagnosis of Influenza -- 9. Animal Influenza: Ecology and Disease -- IV. Epidemiology, Surveillance, And Control -- 10. The Epidemiology of Influenza -- 11. The Control of Influenza

Medicine Medical microbiology Public health Infectious diseases Pathology Epidemiology Plant science Botany Medicine & Public Health Infectious Diseases Pathology Public Health Epidemiology Medical Microbiology Plant Sciences


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