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TitleNeuroendocrine Molecular Biology [electronic resource] / edited by G. Fink, A. J. Harmar, Kenneth W. McKerns
ImprintBoston, MA : Springer US, 1986
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Descript XII, 498 p. online resource


Molecular Biology of the Nervous System -- Structure, Function and Expression of the Human Calcitonin /?-CGRP Gene -- Neuronal Specific Gene Expression in the Murine Hippocampus -- Hybridization Histochemistry โ{128}{148} Locating Gene Expression -- The Identification and Function of Differentiation Antigens on Primary Sensory Neurons -- LHRH โ{128}{148} New Perspectives -- The Physiological Actions of LHRH: Evidence from the Hypogonadal (hpg) Mouse -- The Biosynthetic Precursor of Gonadotropin โ{128}{148} Releasing Hormone: A Multifunctional Prohormone -- Gonadotropin-Releasing Hormone: Differentiation of Structure and Function During Evolution -- The Biosynthesis of LHRH -- Evidence for Sex Differences in GnRH Receptors and Mechanism of Action -- The Role of Brain Peptides in the Control of Anterior Pituitary Hormone Secretion -- Phospholipid Turnover, Ca2+ Mobilization and Protein Kinase C Activation in GnRH Action on Pituitary Gonadotrophs -- Hormonal Regulation of Pituitary Gonadotropin Gene Expression -- Neuropeptides -- The Mammalian Tachykinins and Their Receptors: Structure-Activity Relationship of the Manmalian Tachykinins -- Biosynthesis of the Tachykinins and Somatostatin -- Biosynthesis of Somatostatin, Vasoactive Intestinal Polypeptide, and Thyrotropin Releasing Hormone -- Enzymes Processing Somatostatin โ{128}{148} Precursors, The Somatostatin-28 Convertase of Rat Brain, A System Converting Somatostatin-28 to Both Somatostatins-14 and -28 (1โ{128}{147}12) -- Oxytocin and Vasopressin -- Oxytocin and Vasopressin Secretion: New Perspectives -- Organization and Expression of the Vasopressin and Oxytocin Genes -- Measurement of Expression of the Vasopressin and Oxytocin Genes in Single Neurons by In Situ Hybridization -- Neurohypophysial Peptides in the Gonads -- Molecular Biology of Ovarian Oxytocin -- Characterization, Regulation and Functional Activity of Specific Vasopressin Receptors in the Anterior Pituitary Gland -- Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis -- The Regulation of Proopiomelanocortin Gene Expression by Estrogen in the Rat Hypothalamus -- Differential Regulation of ACTH and ?-Endorphin by Controlled Processing -- Strategies in the Regulation of Secretory Signals from Proopiomelanocortin-Producing Cells -- Expression of Preprosomatostatin Genes in Heterologous Cells -- Degradation of Luteinizing Hormone-Releasing Hormone (LHRH) by Pituitary Plasma Membrane and by Pituitary Cells in Culture -- Neuroendocrine Mechanisms at the Cellular Level -- Analysis of Hormone Secretion from Individual Pituitary Cells -- LHRH Priming in Gonadotrophs: A Model System for the Analysis of Neuroendocrine Mechanisms at the Cellular Level -- Membrane Traffic in Relation with Release Mechanisms in Neuroendocrine Cells in Culture -- Neuro-Steroids: 3?-Hydroxy-?5-Derivatives in the Rat Brain -- Ion Channels and the Control of Secretion in Normal Anterior Pituitary Cells -- Receptors โ{128}{148} Cellular and Molecular Biology -- Biochemical and Functional Characterization of GnRH Receptors -- Hormonal Receptor Plasticity in the Brain as Shown by In Vitro Quantitative Autoradiography -- Cytosolic Factors Modulating Prolactin Binding -- Pituitary GnRH Receptors โ{128}{148} Recent Studies and Their Functional Significance -- Effects of an LHRH Antagonist on Luteal Function in the Macaque -- Clinical Applications -- Comparison of Protein and Ribonucleic Acid Composition of Post Mortem Brain Tissue Between Controls and Cases of Alzheimer Type Dementia -- Neuroendocrine Changes in Alzheimerโ{128}{153}s Disease: Raised Plasma Concentrations of Growth Hormone and Thyroid Stimulating Hormone and Reduced Concentrations of Oestrogen-Stimulated Neurophysin -- The Use of an LHRH Agonist in the Treatment and Investigation of the Premenstrual Syndrome -- Direct Effects of LHRH and Agonists on Human Breast Cancer Cells

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