Title | Regulation of Gene Expression by Hormones [electronic resource] / edited by Kenneth W. McKerns |
---|---|
Imprint | Boston, MA : Springer US : Imprint: Springer, 1983 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-4418-6 |
Descript | XII, 266 p. 44 illus. online resource |
1 Hormone Action in Human Breast Cancer: Estrogen Regulation of Specific Proteins -- 1. Introduction -- 2. Are Breast Tumors True Targets for Estrogen Action? -- 3. Estrogen-Regulated Protein Synthesis in Human Breast Cancer -- 4. Conclusions -- References -- 2 Modulation of an Estrogen-Induced Protein in the MCF7 Human Mammary Cancer Cell -- 1. Introduction -- 2. Estrogen-Induced Proteins Released by MCF7 Cells in Culture -- 3. Dissociated Effect of Nonsteroidal Antiestrogens -- 4. Altered Activation of ER by Antiestrogens -- 5. BrdU Incorporation into DNA Inhibits Estrogen-Induced Responses -- References -- 3 The Estrogen-Induced/Dependent Renal Adenocarcinoma of the Syrian Hamster -- 1. Introduction -- 2. Hypophysectomized Hamsters -- 3. Pituitary Cells in Culture -- 4. Renal Adenocarcinoma Cells in Culture -- 5. Hormone Levels in Hamster Serum -- 6. Tumorogenesis via Immunoendocrine Perturbations -- References -- 4 Stimulation of Milk-Fat Synthesis in Mammary Epithelioid Cells by Progesterone -- 1. Introduction -- 2. Materials and Methods -- 3. Results -- 4. Discussion -- References -- 5 Prolactin and Casein Gene Expression in the Mammary Cell -- 1. Introduction -- 2. The Expression of Casein Genes during Pregnancy and Lactation -- 3. Relation between Casein Synthesis and Casein mRNA Concentration -- 4. The Control of Mammary Cell Hypertrophy -- 5. The Hormonal Control of Casein mRNA Translation -- 6. Variations of Casein Gene Transcription and Casein mRNA Stability -- 7. Relation between Prolactin Receptor Occupancy and the Hormonal Response -- 8. Action of Antiprolactin Receptor Antibodies -- 9. Role of Tubulin-Containing Structures in the Transmission of the Prolactin Message to Casein Genes -- 10. Identification of a Possible Second Messenger for Prolactin -- 11. Conclusions -- References -- 6 Sequential Regulation of Gene Expression by Estrogen in the Developing Rat Uterus -- 1. Introduction -- 2. Sequential Development of Estrogen Responsiveness -- 3. Estrogen-Responsive Creatine Kinase -- 4. Regulation of Glucose-6-Phosphate Dehydrogenase -- 5. Considerations for Future Study -- References -- 7 Estrogen-Induced Uterine Hypertrophy -- 1. Introduction -- 2. Estradiol-17?-Stimulated Uterine Hypertrophy -- 3. Estrogen-Stimulated hnRNA Synthesis and Its Maturation to mRNA -- 4. Studies on the mRNA Population of the Rat Uterus -- 5. Estrogen-Stimulated rRNA and tRNA Synthesis -- 6. The Nature of the Proteins on Which Stimulated Ribosome Production Might Depend -- 7. Investigation of the Mode of Action of the Antiestrogen, Tamoxifen -- References -- 8 Regulation of the Expression of the Uteroglobin Gene by Ovarian Hormones -- 1. Introduction -- 2. Structure and Function of Uteroglobin -- 3. Distribution of Uteroglobin and Differential Hormonal Control -- 4. Hormonal Regulation of Uteroglobin Synthesis: Studies with Isolated Uteri, Endometrial Explants, and Endometrial Cell Cultures -- 5. Characterization of Uteroglobin mRNA and Cell-Free Translation Experiments -- 6. Titration of Uteroglobin mRNA by Molecular Hybridization -- 7. Involvement of the Progesterone Receptor -- 8. Hormonal Regulation of Transcription of the Uteroglobin Gene -- 9. Cloning and Characterization of Uteroglobin cDNA -- 10. Quantitation, Isolation, and Structural Analysis of the Uteroglobin Gene -- 11. Concluding Remarks -- References -- 9 Evolution and Regulation of Genes for Growth Hormone and Prolactin -- 1. Evolution -- 2. Regulation -- References -- 10 Androgenic Control of Gene Expression in Rat Ventral Prostate -- 1. Introduction -- 2. Cloning of Rat Ventral Prostate cDNAs -- 3. Expression of RNA in Ventral Prostate -- 4. Isolation of Prostatic-Binding Protein Genomic Clones -- 5. Characterization of Prostatic-Binding Protein Genes -- 6. Future Prospects -- References -- 11 Effects of Ovarian Steroid Hormones on the Brain and Hypophysis: Receptor Modulation and Chromatin Binding -- 1. Hormonal Modulation of Estrogen and Progesterone Receptors in the Rat Brain -- 2. Chromatin Binding in the Brain and Hypophysis -- 3. Summary and Conclusion -- References -- 12 A Cellular Polyprotein from Bovine Hypothalamus: Structural Elucidation of the Precursor to the Nonapeptide Hormone Arginine Vasopressin -- 1. Introduction -- 2. Structural Organization of the AVPโNP II Precursor -- 3. Primary Structure of the AVPโNP II Common Precursor -- 4. Glycine as Signal for Amidation of Oligopeptides -- 5. The 18K Precursor -- 6. Concluding Remarks -- References